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Haoyuan Chemexpress Co., Ltd.
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021-58950125 |
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info@chemexpress.com |
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Product Name:L-Phenylalanine,N-(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylamino)-,ethyl ester,sulfate (2:1
CAS:1214261-78-5
Purity:>98% Package:17670RMB/100mg
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| Company Name: |
SPIRO PHARMA
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eric_feng1954@126.com |
| Products Intro: |
Product Name:L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1
CAS:1214261-78-5
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1 manufacturers
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| | L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1 Basic information |
| | L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1 Usage And Synthesis |
| Uses | Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester proagent of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2]. | | References | [1] Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91. DOI:10.1124/dmd.115.064436
[2] Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases? Drug Discov Today. 2007 Jul;12(13-14):569-76. DOI:10.1016/j.drudis.2007.05.001 |
| | L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1 Preparation Products And Raw materials |
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