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ME0328

ME0328 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:ME0328
CAS:1445251-22-8
Purity:0.99 Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:ME0328
CAS:1445251-22-8
Purity:0.99 Package:5KG;1KG
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: factory@coreychem.com
Products Intro: Product Name:ME0328
CAS:1445251-22-8
Purity:99% Package:1g;1USD
Company Name: SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Products Intro: Product Name:ME0328
CAS:1445251-22-8
Purity:98% Package:Package as requetsed
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:ME0328
CAS:1445251-22-8
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer

ME0328 manufacturers

  • ME0328
  • ME0328 pictures
  • $1.00 / 1g
  • 2019-12-26
  • CAS:1445251-22-8
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 200kg
ME0328 Basic information
Product Name:ME0328
Synonyms:ME0328;3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide;(S)-3,4-Dihydro-4-oxo-N-(1-phenylethyl)-2-quinazolinepropanamide;ME0328; ME 0328; ME-0328;4-Dihydro-4-oxo-3;4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide;2-Quinazolinepropanamide, 3,4-dihydro-4-oxo-N-[(1S)-1-phenylethyl]-;ME0328 USP/EP/BP
CAS:1445251-22-8
MF:C19H19N3O2
MW:321.37
EINECS:808-923-8
Product Categories:Inhibitors
Mol File:1445251-22-8.mol
ME0328 Structure
ME0328 Chemical Properties
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMSO: soluble10mg/mL, clear
form powder
color white to beige
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
Hazard Codes Xn
Risk Statements 22-43
Safety Statements 36/37
WGK Germany 3
MSDS Information
ME0328 Usage And Synthesis
DescriptionThe poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species. ME0328 is an inhibitor of PARP3 (IC50 = 0.89 μM), which is a regulator of DNA repair and mitotic progression. It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.
UsesME0328 is a potent poly ADP ribose polymerase (PARP) inhibitor with selectivity towards the human ADP-Ribosyltransferase ARTD3/PARP3.
References1) Lindgren?et al. (2013),?PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ART3/PARP3; ACS Chem. Biol.,8?1689
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