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Seratrodast Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Seratrodast
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:112665-43-7
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Seratrodast
Company Name: Jinan Tenglong Chemical Co.,Ltd
Tel: Whatsapp:+8615563263311 Skype:live:smions7080
Products Intro: Product Name:Seratrodast
Purity:99% Remarks:steroids
Company Name: J & K SCIENTIFIC LTD.  
Tel: 400-666-7788 +86-10-82848833
Products Intro: Product Name:Seratrodast, 97%
Purity:97% Package:10MG;50MG
Seratrodast Basic information
Product Name:Seratrodast
Synonyms:benzeneheptanoic acid, -(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-;(+-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoicacid;aa-2414;beta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-bezeneheptanoicaci;5-(2,4,5-trimethyl-3,6,-dioxo-1,4-cyclohexadien-1-yl)benzeneheptanoic acid;7-(3,5,6-trimethy1-1,4-benzoquinon-2-y1)-7-phenylheptanoic acid;7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-1-cyclohexa-1,4-dienyl)heptanoic acid; Abbott 73001
Product Categories:ZAGAM;API;Heterocyclic Compounds;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:112665-43-7.mol
Seratrodast Structure
Seratrodast Chemical Properties
Melting point 118-120°C
storage temp. Store at +4°C
Merck 14,8459
CAS DataBase Reference112665-43-7(CAS DataBase Reference)
Safety Information
RTECS DA1600050
MSDS Information
Seratrodast Usage And Synthesis
DescriptionSeratrodast, a novel benzoquinone derivative, is the first thromboxane A2 (TxA2) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA2, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA2 mimic and by a variety of spasmogenic prostanoids including PGF, PGD2 and 9α,11β-PGF2. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer.
Chemical PropertiesPale Orange Solid
OriginatorTakeda (Japan)
UsesThromboxane A2-receptor antagonist. Antiasthmatic
Brand nameBronica
Biological ActivityThromboxane A 2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA 2 mimetic in guinea pigs.
Seratrodast Preparation Products And Raw materials
Raw materialsPhenol-->Ferric chloride-->Heptanoic acid-->Trimethylhydroquinone-->D-Camphorsulfonic acid
Tag:Seratrodast(112665-43-7) Related Product Information
Cetirizine hydrochloride Ozagrel Cetirizine (R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone Fexofenadine hydrochloride Cyclophosphamide monohydrate 7-PHENYLHEPTANOIC ACID 1,4-HEXADIENE Heptanoic acid