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Seratrodast

Seratrodast Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Seratrodast
CAS:112665-43-7
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:112665-43-7
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Seratrodast
CAS: 112665-43-7
Purity:99% Package:1KG;7USD
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-13650506873
Email: sales@chemdad.com
Products Intro: Product Name:Seratrodast
CAS:112665-43-7
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: 86-18523575427
Email: sales@conier.com
Products Intro: Product Name:seratrodast
CAS:112665-43-7
Purity:0.99 Package:1kg

Lastest Price from Seratrodast manufacturers

  • Seratrodast
  • US $0.01-1.00 / KG
  • 2020-04-25
  • CAS:112665-43-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50 tons
  • Seratrodast
  • US $7.00 / KG
  • 2019-07-06
  • CAS: 112665-43-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
Seratrodast Basic information
Product Name:Seratrodast
Synonyms:50MG/200MG/1G;benzeneheptanoic acid, -(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-;(+-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoicacid;aa-2414;beta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-bezeneheptanoicaci;Seratrodast(AA-2414,ABT-001);AA-2414;SERETRA;AA2414;AA 2414;Seretra
CAS:112665-43-7
MF:C22H26O4
MW:354.44
EINECS:692-169-8
Product Categories:ZAGAM;API;Heterocyclic Compounds;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:112665-43-7.mol
Seratrodast Structure
Seratrodast Chemical Properties
Melting point 118-120°C
Boiling point 522.3±49.0 °C(Predicted)
density 1.140±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
pka4.76±0.10(Predicted)
form Yellow-orange solid.
Merck 14,8459
CAS DataBase Reference112665-43-7(CAS DataBase Reference)
Safety Information
RTECS DA1600050
MSDS Information
Seratrodast Usage And Synthesis
DescriptionSeratrodast, a novel benzoquinone derivative, is the first thromboxane A2 (TxA2) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA2, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA2 mimic and by a variety of spasmogenic prostanoids including PGF, PGD2 and 9α,11β-PGF2. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer.
Chemical PropertiesPale Orange Solid
OriginatorTakeda (Japan)
Usesantibacterial
UsesThromboxane A2-receptor antagonist. Antiasthmatic
Brand nameBronica
Biological ActivityThromboxane A 2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA 2 mimetic in guinea pigs.
Seratrodast Preparation Products And Raw materials
Raw materialsPhenol-->Ferric chloride-->Heptanoic acid-->Trimethylhydroquinone-->D-Camphorsulfonic acid
Tag:Seratrodast(112665-43-7) Related Product Information
Mesna Acetaminophen Ketotifen fumarate Testosterone undecanoate Salbutamol BECLOMETHASONE Thionyl chloride Pemirolast potassium LACOSAMIDE Cetirizine hydrochloride Ozagrel Cetirizine (R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone Fexofenadine hydrochloride Cyclophosphamide monohydrate 7-PHENYLHEPTANOIC ACID 1,4-HEXADIENE Heptanoic acid