| Methyl 2-phenylacetoacetate Chemical Properties |
Melting point | 58.5-59.0 °C | Boiling point | 92-96 °C(Press: 0.6 Torr) | density | 1?+-.0.06 g/cm3(Predicted) | solubility | DMF: 30 mg/ml; DMSO: 50 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 50 mg/ml; Methanol: 1 mg/ml | form | A crystalline solid | pka | 10.67±0.46(Predicted) |
| Methyl 2-phenylacetoacetate Usage And Synthesis |
Uses | Benzeneacetic acid, a-acetyl-, methyl ester can be used as a pharmaceutical raw material. | Description | Methyl 2-phenylacetoacetate is an analytical reference standard categorized as a precursor in the synthesis of amphetamines and methamphetamines. This product is intended for research and forensic applications. The Drug Enforcement Administration is proposing the control of the chemical methyl alpha-phenylacetoacetate (also known as MAPA; methyl 3-oxo-2-phenylbutanoate; methyl 2-phenylacetoacetate; [alpha]-acetyl-benzeneacetic acid, methyl ester; and CAS Number: 16648-44-5) and its optical isomers as a list I chemical under the Controlled Substances Act (CSA). Methyl alpha-phenylacetoacetate is used in clandestine laboratories to illicitly manufacture the schedule II controlled substances phenylacetone (also known as phenyl-2-propanone or P2P), methamphetamine, and amphetamine and is important to the manufacture of these controlled substances. | Description | Methyl 2-phenylacetoacetate (Item No. 28352) is an analytical reference standard categorized as a precursor in the synthesis of amphetamines and methamphetamines. This product is intended for research and forensic applications. | Uses | D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.
Droperidol is a potent antagonist of dopamine subtype 2 receptor. It is an antipsychotic, which is used to treat acute behavioral anomalies. It helps to manage postoperative nausea and vomiting.
Endogenous κ1b opioid receptor agonist. | Preparation | Methyl phenyldiazoacetate, precursor to cyclopropanation agents, is prepared by treating methyl phenylacetate with p-acetamidobenzenesulfonyl azide in the presence of base. |
| Methyl 2-phenylacetoacetate Preparation Products And Raw materials |
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