(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone

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(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone Basic information
Product Name:(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone
Synonyms:(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone;Methanone, [4-amino-2-[(1-methylethyl)amino]-5-thiazolyl]phenyl-;CDK9 inhibitor HH1;CDK9 inhibitor HH1, 10 mM in DMSO
CAS:204188-41-0
MF:C13H15N3OS
MW:261.34
EINECS:
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Mol File:204188-41-0.mol
(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone Structure
(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone Chemical Properties
Boiling point 453.4±55.0 °C(Predicted)
density 1.272±0.06 g/cm3(Predicted)
pka3.17±0.10(Predicted)
form Solid
color Light yellow to yellow
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MSDS Information
(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone Usage And Synthesis
UsesCDK9 inhibitor HH1 is a potent and selectively CDK9 inhibitor. CDK9 inhibitor HH1 inhibits the transcription of CDK. CDK9 inhibitor HH1 can be used in research of cancer[1].
IC 50CDK9
References[1] Pandey S, et, al. Selective CDK9 Inhibition by Natural Compound Toyocamycin in Cancer Cells. Cancers (Basel). 2022 Jul 8;14(14):3340. DOI:10.3390/cancers14143340
(4-amino-2-(isopropylamino)thiazol-5-yl)(phenyl)methanone Preparation Products And Raw materials
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