九聚乙二醇-叔丁氧羰基
中文名称 | 九聚乙二醇-叔丁氧羰基 |
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中文同义词 | 九聚乙二醇-叔丁氧羰基;叔丁氧酰胺-九聚乙二醇;氨基叔丁酯-九聚乙二醇-羟基;叔丁氧羰基九聚乙二醇羟基;叔丁氧羰基九聚乙二醇;(26-羟基-3,6,9,12,15,18,21,24-八氧杂二十六烷基)氨基甲酸叔丁酯;氨基叔丁酯-九聚乙二醇;叔丁氧羰基-PEG9-羟基 |
英文名称 | N-Boc-PEG9-alcohol |
英文同义词 | N-Boc-PEG9-alcohol;tert-Butyl (26-hydroxy-3,6,9,12,15,18,21,24-octaoxahexacosyl)carbamate;t-boc-N-amido-PEG9-alcohol;5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanoic acid, 28-hydroxy-, 1,1-dimethylethyl ester;CAS_2112731-44-7;NHBoc-PEG9-OH;BocNH-PEG9-OH;BocNH-PEG9-alcohol |
CAS号 | 2112731-44-7 |
分子式 | C23H47NO11 |
分子量 | 513.62 |
EINECS号 | |
相关类别 | 其它;助剂 |
Mol文件 | 2112731-44-7.mol |
结构式 |
九聚乙二醇-叔丁氧羰基 性质
沸点 | 585.1±50.0 °C(Predicted) |
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密度 | 1.095±0.06 g/cm3(Predicted) |
溶解度 | 溶于水、DMSO、DCM、DMF |
酸度系数(pKa) | 12.23±0.46(Predicted) |
Cleavable
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PEGs
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Alkyl/ether
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.