| Company Name: |
Shanghai Standard Technology Co.,Ltd.
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021-57127007-6622 15618937986 |
| Email: |
zhaok@nature-standard.com |
| Products Intro: |
Product Name:lup-28-al-20(29)-en-3-one
CAS:4439-98-9
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| Company Name: |
ChemeGen 中国
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| Tel: |
18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:Betulonaldehyde
CAS:4439-98-9
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
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customer_service@efebio.com |
| Products Intro: |
Product Name:Betulonaldehyde
CAS:4439-98-9
Purity:95% Package:10mg;50mg;100mg
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| | betulonic aldehyde Basic information |
| Product Name: | betulonic aldehyde | | Synonyms: | betulonic aldehyde;Betulonic aldehyde, 97%, Semi-Synthetic;Betulonaldehyde;lup-28-al-20(29)-en-3-one;Lup-20(29)-en-28-al, 3-oxo-;(1R,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-9-oxoicosahydro-3aH-cyclopenta[a]chrysene-3a-carbaldehyde | | CAS: | 4439-98-9 | | MF: | C30H46O2 | | MW: | 438.68 | | EINECS: | | | Product Categories: | | | Mol File: | 4439-98-9.mol |  |
| | betulonic aldehyde Chemical Properties |
| Melting point | 165-166 °C | | Boiling point | 511.7±33.0 °C(Predicted) | | density | 1.037±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMF: 10 mg/ml | | form | A crystalline solid |
| | betulonic aldehyde Usage And Synthesis |
| Biological Activity | Betulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula.1 It is active against P. falciparum (IC50 = 3.36 μg/ml) and cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s = 19.23 and 17.09 μg/ml, respectively).2 Topical application of betulonaldehyde (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate in mice.3 It has also been used a precursor in the semisynthesis of C-2 and C-28 betulonic aldehyde derivatives.1 | | References | 1.Ayers, S., Benkovics, T., Marshall, J., et al.Autoxidation products of betulonaldehydeJ. Nat. Prod.79(10)2758-2761(2016)
2.Wisetsai, A., Schevenels, F.T., and Lekphrom, R.Chemical constituents and their biological activities from the roots of diospyros filipendulaNat. Prod. Res.1-5(2019)
3.Yasukawa, K., Yu, S., Yamanouchi, S., et al.Some lupane-type triterpenes inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skinPhytomedicine1(4)309-313(1995) |
| | betulonic aldehyde Preparation Products And Raw materials |
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