RWJ-51204

Request For Quotation
RWJ-51204 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:RWJ-51204
CAS:205701-85-5
Purity:99.57% Package:1mg;350USD|5mg;828USD|10mg;1130USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:RWJ-51204
CAS:205701-85-5
Purity:97.0% Package:5mg
Company Name: Beijing xinyanhui pharmaceutical research and development co., LTD  
Tel: 13969155946
Email: 1461866103@qq.com
Products Intro: CAS:205701-85-5
Purity:99% HPLC Package:5KG;1KG；500G;100G;50G
Company Name: cjbscvictory  
Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Products Intro: Product Name:RWJ-51204
CAS:205701-85-5
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Products Intro: Product Name:RWJ-51204
CAS:205701-85-5
Purity:98% Package:1mg

RWJ-51204 manufacturers

  • RWJ-51204
  • RWJ-51204 pictures
  • $210.00
  • 2026-05-23
  • CAS:205701-85-5
  • Purity: 99.95%
  • Supply Ability: 10g
RWJ-51204 Basic information
Product Name:RWJ-51204
Synonyms:RWJ-51204;Pyrido[1,2-a]benzimidazole-4-carboxamide, 5-(ethoxymethyl)-7-fluoro-N-(2-fluorophenyl)-1,2,3,5-tetrahydro-3-oxo-;RWJ51204,RWJ 51204;RWJ-51204, 10 mM in DMSO
CAS:205701-85-5
MF:C21H19F2N3O3
MW:399.39
EINECS:
Product Categories:
Mol File:205701-85-5.mol
RWJ-51204 Structure
RWJ-51204 Chemical Properties
Boiling point 533.0±50.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka10.81±0.70(Predicted)
Safety Information
MSDS Information
RWJ-51204 Usage And Synthesis
UsesRWJ-51204 is a partial agonist of GABA(A) receptor, with Ki of 0.2-2 nM to the benzodiazepine site on GABA(A) receptors.
in vivo

RWJ-51204 is orally active in anxiolytic efficacy tests. WJ 51204 dose-relatedly antagonizes PTZ-induced clonic convulsions when administered orally (ED50 = 0.04 mg/kg). RWJ-51204 is effective in the conflict test in monkeys (ED50 of approximately 0.5 mg/kg p.o.). RWJ-51204 potently impairs rotarod performance in rats (ED50 = 0.12 mg/kg), and all rats given RWJ-51204 orally at 30 mg/kg exhibit sedation, reduced skeletal muscle tone, and impairment of rotarod performance.

References[1] Dubinsky B, et al. 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic. J Pharmacol Exp Ther. 2002 Nov;303(2):777-90. DOI:10.1124/jpet.102.036954
RWJ-51204 Preparation Products And Raw materials
Tag:RWJ-51204(205701-85-5) Related Product Information