M-3M3FBS

M-3M3FBS Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:m-3M3FBS
CAS:200933-14-8
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:m-3M3FBS
CAS:200933-14-8
Purity:98% Package:10mg Remarks:V24871
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:m-3M3FBS
CAS:200933-14-8
Package:10 mg;100 mg;200 mg;25 mg;5 mg;50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:M-3M3FBS;2,4,6-TriMethyl-N-[3-(trifluoroMethyl)phenyl]benzenesulfonaMide
CAS:200933-14-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: Alfa Aesar  
Tel: 400-6106006
Email: saleschina@alfa-asia.com
Products Intro: Product Name:2,4,6-TriMethyl-N-[3-(trifluoroMethyl)phenyl]benzenesulfonaMide, 97%
CAS:200933-14-8
Package:25Mg Remarks:H55920
M-3M3FBS Basic information
Product Name:M-3M3FBS
Synonyms:N-(3-TRIFLUOROMETHYLPHENYL)-2,4,6-TRIMETHYLBENZENESULFONAMIDE;2,4,6-TRIMETHYL-N-(3-(TRIFLUOROMETHYL)PH;Phospholipase C Activator,;M-3M3FBS;2,4,6-TRIMETHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZENESULFONAMIDE;2,4,6-TRIMETHYL-N-(M-3-TRIFLUOROMETHYLPHENYL)BENZENESULFONAMIDE;Phospholipase C Activator, m-3M3FBS - CAS 200933-14-8 - Calbiochem;Benzenesulfonamide, 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]-
CAS:200933-14-8
MF:C16H16F3NO2S
MW:343.36
EINECS:
Product Categories:Lipid signaling
Mol File:200933-14-8.mol
M-3M3FBS Structure
M-3M3FBS Chemical Properties
Melting point 114-114.8 °C(lit.)
Boiling point 420.0±55.0 °C(Predicted)
density 1.316±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO: 92 mg/mL
form solid
pka7.82±0.10(Predicted)
color white
Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
M-3M3FBS Usage And Synthesis
Descriptionm-3M3FBS (200933-14-8) is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca2+ release and inositol phosphate release in a variety of cell types.1?Inhibits growth of U937 and THP-1 cells.2 m-3M3FBS also affects calcium homeostasis independently of PLC activation.3
Usesm-3M3FBS is used in biological studies as phospholipase C activator m-3M3FBS effects on Ca2+ homeostasis independently of phospholipase C activation.
Usesm-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis1. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells2.
DefinitionChEBI: 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide is a sulfonamide.
Biological ActivityActivator of phospholipase C (PLC). Stimulates superoxide generation, Ca 2+ release and inositol phosphate formation in a variety of cell types.
Biochem/physiol ActionsFirst known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms).
storageStore at RT
References1) Bae?et al. (2003),?Identification of a compound that directly stimulates phospholipase C activity; Mol. Pharmacol.,?63?1043 2) Lee?et al. (2005),?The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis; Cancer Lett.,?222?227 3) Krjukova?et al. (2004),?Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation; Br. J. Pharmacol.,?143?3
M-3M3FBS Preparation Products And Raw materials
Tag:M-3M3FBS(200933-14-8) Related Product Information
Brilliant Pink FBS FBS, Fetal Bovine Serum,FBS GOLD,FBS SILVER,FBS Benzenesulfonamide, 2,4,6-trimethyl- (9CI) P-TOLUENESULFONANILIDE M-3M3FBS O-3M3FBS CELLECT FBS GOLD GRACE'S INSECT MEDIUM W/O FBS 2-methyl-N-phenylbenzenesulfonamide FBS gamma -Irradiated USA origin FBS USA origin FBS Heat Inactivated CANADIAN origin FBS Heat Inactivated EU approved FBS gamma -Irradiated AUSTRALIAN origin FBS ES cell tested USA origin FBS low IgG EU approved FBS Dialysed AUSTRALIAN origin FBS Dialysed CANADIAN origin