Related articles - A cinacalcet analog-Evocalcet
- Evocalcet, a novel oral calcimimetic agent, is an allosteric modulator that acts on the calcium-sensing receptors on the membr....
- Dec 26，2023
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| | Evocalcet Basic information |
| Product Name: | Evocalcet | | Synonyms: | Evocalcet;KHK7580;Benzeneacetic acid, 4-[(3S)-3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-;2-{4-[(3S)-3-{[(1R)-1-(Naphthalen-1-yl)ethyl]amino}pyrrolidin-1-yl]phenyl}acetic acid;Calcium-sensing receptor,KHK-7580,Inhibitor,KHK 7580,CaSR,Evocalcet,inhibit;Ivocase;MT 4580;MT4580 | | CAS: | 870964-67-3 | | MF: | C24H26N2O2 | | MW: | 374.48 | | EINECS: | | | Product Categories: | | | Mol File: | 870964-67-3.mol |  |
| | Evocalcet Chemical Properties |
| Boiling point | 594.4±50.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF:5.0(Max Conc. mg/mL);13.35(Max Conc. mM)
DMSO:5.0(Max Conc. mg/mL);13.35(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.81(Max Conc. mM) | | form | A crystalline solid | | pka | 4.71±0.10(Predicted) |
| | Evocalcet Usage And Synthesis |
| Uses | 4-[(3S)-3-[[(1R)-1-(1-Naphthalenyl)ethyl]amino]-1-pyrrolidinyl]benzeneacetic Acid is part of a pharmaceutical composition that is a therapeutic agent for hyperparathyroidism. |
| | Evocalcet Preparation Products And Raw materials |
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