| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
|
| Tel: |
010-60605840 18892239720 |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide
CAS:529493-92-3
Package:100mg;250mg;500mg
|
| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
025-85563444 18351873721 |
| Email: |
purchase@synzest.com |
| Products Intro: |
Product Name:CYAYKKUWALRRPA-UHFFFAOYSA-N
CAS:529493-92-3
Purity:95%HPLC Package:50mg;100mg;250mg;1g
|
| Company Name: |
Zhengzhou Akem Chemical Co., Ltd
|
| Tel: |
13303867194 |
| Email: |
3001317055@qq.com |
| Products Intro: |
Product Name:2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide
CAS:529493-92-3
Purity:95% Package:250mg；500mg；1g；5g
|
|
| | CYAYKKUWALRRPA-UHFFFAOYSA-N Basic information |
| Product Name: | CYAYKKUWALRRPA-UHFFFAOYSA-N | | Synonyms: | CYAYKKUWALRRPA-UHFFFAOYSA-N;Hexopyranosyl bromide, 2,3,4,6-tetraacetate;6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide;2,3,4,6 Tetra o acetyl alpha galactosylpyranosyl bromide,PROTAC Linkers,2,3,4,6Tetraoacetylalphagalactosylpyranosyl bromide,Inhibitor,inhibit | | CAS: | 529493-92-3 | | MF: | C14H19BrO9 | | MW: | 411.2 | | EINECS: | | | Product Categories: | | | Mol File: | 529493-92-3.mol |  |
| | CYAYKKUWALRRPA-UHFFFAOYSA-N Chemical Properties |
| | CYAYKKUWALRRPA-UHFFFAOYSA-N Usage And Synthesis |
| Biological Activity | 2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | CYAYKKUWALRRPA-UHFFFAOYSA-N Preparation Products And Raw materials |
|