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| Ethyl 2-hydroxyisobutyrate Basic information |
| Ethyl 2-hydroxyisobutyrate Chemical Properties |
Hazard Codes | Xi | Risk Statements | 10-36/37/38-36/38 | Safety Statements | 26-36-16 | RIDADR | UN 3272 3/PG 3 | WGK Germany | 3 | RTECS | OD5672000 | HazardClass | 3 | PackingGroup | III | HS Code | 29181980 |
| Ethyl 2-hydroxyisobutyrate Usage And Synthesis |
Description | Ethyl 2-hydroxyisobutyrate (E-2HIBA) has a wide range of applications in flavor and fragrance ingredients, green solvents, and pharmaceuticals. E-2HIBA has been synthesized by the batch transesterification of methyl 2-hydroxyisobutyrate with ethanol in the presence of titanium tetraethoxide (reaction conditions: 96 h, yield 97 %) and the esterification of 2-HIBA with an acid catalyst. The direct esterification of 2-HIBA with ethanol using an acid catalyst appears to be a commercially viable approach to produce E-2HIBA [1].
| Chemical Properties | clear colorless liquid | Uses | Solvent for nitrocellulose and cellulose acetate; solvent mixture for cellulose ethers, organic synthesis, pharmaceuticals. | References | [1] Sripada, Sarada and James R. Kastner. “Continuous catalytic esterification using a solid acid activated carbon monolith: Comparison of granular and monolith forms with a commercial catalyst.” Chemical Engineering Journal 43 29 (2023): 0.
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| Ethyl 2-hydroxyisobutyrate Preparation Products And Raw materials |
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