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| | Boc-5-aminopentanoic acid Basic information |
| Product Name: | Boc-5-aminopentanoic acid | | Synonyms: | N-T-BUTOXYCARBONYL-5-AMINOPENTANOIC ACID;N-DELTA-T-BUTOXYCARBONYL-DELTA-AMINOVALERIC ACID;N-BOC-5-AMINOPENTANOIC ACID;N-BOC-5-AMINOVALERIC ACID;PENTANOIC ACID, 5-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-;RARECHEM EM WB 0073;5-(TERT-BUTOXYCARBONYLAMINO)PENTANOIC ACID;5-(BOC-AMINO)PENTANOIC ACID | | CAS: | 27219-07-4 | | MF: | C10H19NO4 | | MW: | 217.26 | | EINECS: | | | Product Categories: | | | Mol File: | 27219-07-4.mol |  |
| | Boc-5-aminopentanoic acid Chemical Properties |
| Melting point | 48-52 °C(lit.) | | Boiling point | 160-168 °C0.8 mm Hg(lit.) | | density | 1.1518 (rough estimate) | | refractive index | 1.4500 (estimate) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | Powder | | pka | 4.72±0.10(Predicted) | | color | Off-white | | BRN | 2048862 | | CAS DataBase Reference | 27219-07-4(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | F | 10-21 | | HazardClass | IRRITANT | | HS Code | 29241990 |
| | Boc-5-aminopentanoic acid Usage And Synthesis |
| Description | Boc-5-aminopentanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Boc-5-aminopentanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | | Chemical Properties | solid | | Uses | Boc-5-aminovaleric acid can be used to synthesize inhibitors of bacterial quorum seining and biofilm formation. It can also be used to synthesize diblock and triblock copolymers. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 48, p. 2424, 1983 DOI: 10.1021/jo00162a028 |
| | Boc-5-aminopentanoic acid Preparation Products And Raw materials |
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