- Fenofibric acid
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2025-06-18
- CAS:42017-89-0
- Min. Order:
- Purity: 0.99
- Supply Ability:
- Fenofibric acid
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- $10.00 / 1KG
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2025-06-12
- CAS:42017-89-0
- Min. Order: 100KG
- Purity: 99%
- Supply Ability: 100 mt
- Fenofibric acid
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- $29.00 / 1mL
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2025-06-10
- CAS:42017-89-0
- Min. Order:
- Purity: 99.94%
- Supply Ability: 10g
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| | Fenofibric acid Basic information |
| | Fenofibric acid Chemical Properties |
| Melting point | 177-179°C | | Boiling point | 486.5±35.0 °C(Predicted) | | density | 1.286±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 3.09±0.10(Predicted) | | form | powder | | color | White to Off-White | | BRN | 2058973 | | InChI | InChI=1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21) | | InChIKey | MQOBSOSZFYZQOK-UHFFFAOYSA-N | | SMILES | C(O)(=O)C(OC1=CC=C(C(=O)C2=CC=C(Cl)C=C2)C=C1)(C)C | | CAS DataBase Reference | 42017-89-0(CAS DataBase Reference) |
| Hazard Codes | Xn,N | | Risk Statements | 36/37/38-50/53-22 | | Safety Statements | 26-36/37/39-61-60-24/25 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 | | RTECS | UA2453000 | | HazardClass | 9 | | PackingGroup | III | | HS Code | 29189900 | | Toxicity | LD50 oral in rat: 1242mg/kg |
| | Fenofibric acid Usage And Synthesis |
| Chemical Properties |
Fenofibric acid is a white to almost white crystalline powder that is stable under ordinary conditions and has a melting point of 179 – 183°C. Its empirical formula is C17H15ClO4 and molecular weight 318.75. Fenofibric acid is insoluble in water; its solubility increases with pH in buffered media.
| | Uses | DPP4 inhibitor, antidiabetic | | Uses | Fenofibric acid, the active metabolite of fenofibrate. Increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner. | | Uses | Fenofibric acid, the active metabolite of fenofibrate. Increases Apolipoprotein A-Iediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptorependent manner | | Definition | ChEBI: A monocarboxylic acid that is 2-methylpropanoic acid substituted by a 4-(4-chlorobenzoyl)phenoxy group at position 2. It is a metabolite of the drug fenofibrate. | | Metabolism | Fenofibric acid is primarily conjugated with glucuronic acid and then excreted in urine. A small amount of fenofibric acid is reduced at the carbonyl moiety to a benzhydrol metabolite, which is, in turn, conjugated with glucuronic acid and excreted in urine. In vitro and in vivo metabolism data indicate that fenofibric acid does not undergo oxidative metabolism (e.g. cytochrome P450) to a significant extent. The enzymes CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4 do not play a role in the metabolism of fenofibric acid. |
| | Fenofibric acid Preparation Products And Raw materials |
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