- L-4-Abu-Ome.Hcl
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- $0.00 / 1kg
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2026-04-24
- CAS:13031-60-2
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | Methyl 4-aminobutyrate hydrochloride Basic information |
| | Methyl 4-aminobutyrate hydrochloride Chemical Properties |
| Melting point | 120-125 °C(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to crystal | | color | White to Almost white | | BRN | 3558996 | | Major Application | peptide synthesis | | InChI | InChI=1S/C5H11NO2.ClH/c1-8-5(7)3-2-4-6;/h2-4,6H2,1H3;1H | | InChIKey | WPGPRLVPWACBHW-UHFFFAOYSA-N | | SMILES | C(=O)(OC)CCCN.Cl |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37 | | WGK Germany | 3 | | RTECS | ES7065000 | | F | 3 | | HazardClass | IRRITANT | | HS Code | 2922498590 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | Methyl 4-aminobutyrate hydrochloride Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Uses | Methyl 4-aminobutyrate, HCl | | reaction suitability | reaction type: solution phase peptide synthesis | | Synthesis | GENERAL METHOD: Thionyl chloride (20 mmol) was added slowly and dropwise to a 20 mL methanol solution of gamma-aminobutyric acid (10 mmol) under ice bath conditions. The reaction mixture was stirred at room temperature for about 2 h before the solvent was removed by rotary evaporator to give methyl 4-aminobutyrate hydrochloride (11a). The product was a white solid in 96.0% yield.1H NMR (400 MHz, D2O) δ 3.46 (s, 3H), 2.79 (t, J = 7.6 Hz, 2H), 2.28 (t, J = 7.3 Hz, 2H), 1.77-1.67 (m, 2H).ESI-MS analysis showed that the calculated value of [M + H-HCl]+ m/z was 118.1 and the measured value was 118.1. | | References | [1] Journal of Medicinal Chemistry, 1984, vol. 27, # 10, p. 1263 - 1267
[2] Synthetic Communications, 1998, vol. 28, # 3, p. 471 - 474
[3] Tetrahedron Letters, 2005, vol. 46, # 47, p. 8137 - 8140
[4] Chemistry - A European Journal, 2012, vol. 18, # 18, p. 5767 - 5776
[5] Journal of Medicinal Chemistry, 2006, vol. 49, # 20, p. 6094 - 6103 |
| | Methyl 4-aminobutyrate hydrochloride Preparation Products And Raw materials |
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