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| | BENZYL 2,2,2-TRICHLOROACETIMIDATE Basic information |
| Product Name: | BENZYL 2,2,2-TRICHLOROACETIMIDATE | | Synonyms: | 2,2,2-TRICHLOROACETIMIDIC ACID BENZYL ESTER;Benzyl 2,2,2-trichloroacetimidate, 98+%;Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester;Benzyl 2,2,2-trichloroacetimidate, GC 99%;BENZYLPHOSPONIC ACID;Benzyl 2,2,2-trichloroethanimidoate;TRICHLOROACETIMIDIC ACID BENZYL ESTER;LABOTEST-BB LT00455324 | | CAS: | 81927-55-1 | | MF: | C9H8Cl3NO | | MW: | 252.52 | | EINECS: | | | Product Categories: | Protection & Derivatization Reagents (for Synthesis);Synthetic Organic Chemistry;Amidates/Imidates;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Benzene series | | Mol File: | 81927-55-1.mol |  |
| | BENZYL 2,2,2-TRICHLOROACETIMIDATE Chemical Properties |
| Melting point | 3 °C | | Boiling point | 106-114 °C0.5 mm Hg(lit.) | | density | 1.359 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.545(lit.) | | Fp | >230 °F | | storage temp. | 2-8°C | | solubility | Miscible with cyclohexane/dichloromethane. | | form | Liquid | | pka | 2.23±0.70(Predicted) | | color | Clear colorless to yellow | | Sensitive | Moisture Sensitive | | BRN | 2525375 | | Stability: | Moisture Sensitive | | CAS DataBase Reference | 81927-55-1(CAS DataBase Reference) |
| | BENZYL 2,2,2-TRICHLOROACETIMIDATE Usage And Synthesis |
| Chemical Properties | clear colorless to yellow liquid | | Uses | Benzyl 2,2,2-trichloroacetimidate was used as reagent during the synthesis of funiculosin dimethyl ether and (S)-3-(benzyloxy)-2-methylpropanal. It was used in the acid-catalyzed benzylation of hydroxy groups. | | Uses | Benzyl 2,2,2-trichloroacetimidate is used for the acid-catalyzed benzylation of hydroxy groups. It acts as reagent during the synthesis of funiculosin dimethyl ether and (S)-3-(benzyloxy)-2-methylpropanal. It can also be used for mild esterification of carboxylic acids in the presence of a catalytic amount of BF3 etherate. | | Uses | Benzyl 2,2,2-trichloroacetimidate is used for the acid-catalyzed benzylation of hydroxy groups. | | Purification Methods | Purify the imidate by distillation to remove up to 1% of PhCH2OH as stabiliser. A solution in hexane can be stored for up to 2 months without decomposition. It is hygroscopic and has to be stored dry. [Wessel et al. J Chem Soc, Perkin Trans 1 2247 1985, Beilstein 6 IV 2265.] |
| | BENZYL 2,2,2-TRICHLOROACETIMIDATE Preparation Products And Raw materials |
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