ANTI-PHOSPHO-TAU (PSER404)

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ANTI-PHOSPHO-TAU (PSER404) Suppliers list
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
ANTI-PHOSPHO-TAU (PSER404) Basic information
Product Name:ANTI-PHOSPHO-TAU (PSER404)
Synonyms:Anti-phospho-Tau (pSer404) antibody produced in rabbit;ANTI-PHOSPHO-TAU (PSER404)
CAS:
MF:
MW:0
EINECS:
Product Categories:Alphabetical Index;Antibodies for Alzheimer and Neurodegenerative Disease ResearchCell Biology;Antibodies for Neurobiology;Antibodies for Neurodegenerative Diseases Research;Antibodies to Cytoskeleton;Antibodies to Microtubule and Associated ProteinsAntibodies
Mol File:Mol File
ANTI-PHOSPHO-TAU (PSER404) Structure
ANTI-PHOSPHO-TAU (PSER404) Chemical Properties
storage temp. -20°C
form buffered aqueous glycerol solution
biological sourcerabbit
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 1
MSDS Information
ProviderLanguage
SigmaAldrich English
ANTI-PHOSPHO-TAU (PSER404) Usage And Synthesis
UsesAnti-phospho-Tau (pSer404) antibody may be used in western blot (1:1000), immunoblot (1:1000) and immunohistochemistry.
General DescriptionTau is a microtubule-associated phosphoprotein that is present in the axons of nerve cells. It stabilizes microtubules and mediates the polymerization of tubulin. Phosphorylation of Tau regulates its cellular functions. Hyperphosphorylation of Tau has been linked to neurodegenerative disorders such as Alzheimer′s disease . Anti-phospho-Tau (pSer404) antibody specifically reacts with Tau (pSer404) (45-68 kDa) in humans, mice and rats.
Biological ActivityMAPT (microtubule associated protein tau) participates in the pathology of Alzheimerμs disease (AD). It helps in the assembly and maintenance of microtubule structure. Removal of MAPT results in developmental delay and learning disability.
ANTI-PHOSPHO-TAU (PSER404) Preparation Products And Raw materials
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