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| Product Name: | AA9 | | Synonyms: | SRS11-92;Benzoic acid, 4-(cyclohexylamino)-3-[(phenylmethyl)amino]-, ethyl ester;HT-1080,FRDA,Friedreich,Inhibitor,cell death,ataxia,SRS-11-92,SRS1192,Ferroptosis,inhibit,SRS11 92,SRS11-92 | | CAS: | 1467047-25-1 | | MF: | C22H28N2O2 | | MW: | 352.47 | | EINECS: | | | Product Categories: | | | Mol File: | 1467047-25-1.mol |  |
| Boiling point | 523.7±45.0 °C(Predicted) | | density | 1.152±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml | | form | A crystalline solid | | pka | 5.48±0.20(Predicted) |
| Definition | ChEBI: SRS11-92 is an ethyl ester resulting from the formal condensation of the carboxy group of 3-(benzylamino)-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis induced by erastin in HT-1080 human fibrosarcoma cells (EC50 = 6 nM). It has a role as a ferroptosis inhibitor. It is a substituted aniline, an ethyl ester, a secondary amino compound and a diamine. It is functionally related to a ferrostatin-1. |
| | AA9 Preparation Products And Raw materials |
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