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Product Name:C18 Ceramide-d3 (d18:1/18:0-d3)
CAS:2011762-82-4
Purity:99% Package:1mg
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Alfa Chemistry
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1-516-6625404 |
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Product Name:C18 Ceramide-d3 (d18:1/18:0-d3)
CAS:2011762-82-4
Purity:99%+ Package:1g;10g;100g;1KG;5KG
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:C18 Ceramide-d3 (d18:1/18:0-d3)
CAS:2011762-82-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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| Products Intro: |
Product Name:C18 Ceramide-d3 (d18:1/18:0-d3)
CAS:2011762-82-4
Purity:>95% Package:1mg
|
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| | C18 Ceramide-d3 (d18:1/18:0-d3) Basic information |
| | C18 Ceramide-d3 (d18:1/18:0-d3) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Chloroform: Soluble,DMF: Soluble,Ethanol: Warmed | | form | A solid |
| | C18 Ceramide-d3 (d18:1/18:0-d3) Usage And Synthesis |
| Biological Activity | C18 Ceramide-d3 (d18:1/18:0) is intended for use as an internal standard for the quantification of C18 Ceramide (d18:1/18:0) by GC- or LC-MS. C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.1 Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells.2 It is selectively downregulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.3 [Matreya, LLC. Catalog No. 2201] | | References | 1.Mizutani, Y., Kihara, A., and Igarashi, Y.Mammalian Lass6 and its related family members regulate synthesis of specific ceramidesBiochem J.390(Pt. 1)263-271(2005)
2.Koybasi, S., Senkal, C.E., Sundararaj, K., et al.Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomasJ. Biol. Chem.279(43)44311-44319(2004)
3.Bergman, B.C., Brozinick, J.T., Strauss, A., et al.Muscle sphingolipids during rest and exercise: A C18:0 signature for insulin resistance in humansDiabetologia59(3)785-791(2016) |
| | C18 Ceramide-d3 (d18:1/18:0-d3) Preparation Products And Raw materials |
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