| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:DSP-1053;DSP1053,DSP 1053
CAS:1176326-76-3
Purity:98% Package:10 mg;5 mg
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| Company Name: |
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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| Tel: |
021-59167510 18117107507 |
| Email: |
vip@med-life.cn |
| Products Intro: |
Product Name:DSP-1053
CAS:1176326-76-3
Purity:>=99% Package:10mg;100mg;10mM*1mLinDMSO;5mg;50mg
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| | DSP-1053 Basic information |
| Product Name: | DSP-1053 | | Synonyms: | DSP-1053;4H-1-Benzopyran-4-one, 6-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-piperidinyl]ethyl]-2,3-dihydro- | | CAS: | 1176326-76-3 | | MF: | C26H32BrNO4 | | MW: | 502.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1176326-76-3.mol |  |
| | DSP-1053 Chemical Properties |
| Boiling point | 610.7±55.0 °C(Predicted) | | density | 1.294±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (199.03 mM; Need ultrasonic) | | pka | 9.06±0.10(Predicted) |
| | DSP-1053 Usage And Synthesis |
| Biological Activity | DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity[1]. | | References | [1]. Yoshinaga H, et al. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity. Bioorg Med Chem. 2018 May 1;26(8):1614-1627. |
| | DSP-1053 Preparation Products And Raw materials |
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