- Palmatine hcl
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- $0.00 / 25kg
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2023-08-05
- CAS:10605-02-4
- Min. Order: 1kg
- Purity: CP2020
- Supply Ability: 10tons
- Palmatine hydrochloride
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- $0.00 / 20mg
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2023-02-24
- CAS:10605-02-4
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Palmatine hydrochloride
-
- $0.00 / 20mg
-
2023-02-24
- CAS:10605-02-4
- Min. Order: 5mg
- Purity: Analytical Standard
- Supply Ability: 10 g
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| | Palmatine chloride Basic information |
| Product Name: | Palmatine chloride | | Synonyms: | 2,3,9,10-TETRAMETHOXYPROTOBERBERINCHLORIDE;BERBERICINE CHLORIDE;PALMATINE CHLORIDE;Palmatine HCL;PalMatin hydrochloride;2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride;Palmatine chloride
2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride;(947153-64-2) palmatine chloride | | CAS: | 10605-02-4 | | MF: | C21H22ClNO4 | | MW: | 387.86 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors | | Mol File: | 10605-02-4.mol |  |
| | Palmatine chloride Chemical Properties |
| Melting point | 205℃ | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | Chloroform (Slightly), DMSO (Slightly) | | form | Solid | | color | Yellow | | InChI | InChI=1S/C21H22NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,9-12H,7-8H2,1-4H3;1H/q+1;/p-1 | | InChIKey | RLQYRXCUPVKSAW-UHFFFAOYSA-M | | SMILES | C12=CC3=C(C(OC)=C(OC)C=C3)C=[N+]1CCC1C=C(OC)C(OC)=CC2=1.[Cl-] |
| | Palmatine chloride Usage And Synthesis |
| Description | Corydalis paUida yields this alkaloid which occurs in the quaternary base fraction.
The alkaloid is separated by droplet countercurrent chromatography and crystallizes from H20 as yellow-green needles. | | Description | Palmatine is an alkaloid that has been found in C. rhizoma and has diverse biological activities. It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 0.51 and 6.84 μM, respectively). Palmatine (20, 40, and 80 μM) reduces Zika virus infection of Vero cells in a concentration-dependent manner. In vivo, palmatine (50 and 100 mg/kg) reduces colonic myeloperoxidase (MPO) activity and IL-10, IL-1β, IL-6, and TNF-α levels, as well as protects mucosal integrity in a mouse model of colitis induced by dextran sulfate (DSS; ). It reduces stomach ulcer area in a rat model of acetic acid-induced gastric ulcers. Palmatine (10 and 20 mg/kg) reduces the number of small intestine and colon tumors in the ApcMin+/- mouse model of multiple intestinal neoplasia. | | Uses | antibacterial, antimalarial, uterine contractant | | Uses | Palmatine Chloride is a protoberberine alkaloid, as a potential anti-inflammatory and anti-hypertensive agent. | | target | Antifection | | References | Tani, Nakagura, Hattori, Yakugaku Zasshi, 95, 1103 (1975) |
| | Palmatine chloride Preparation Products And Raw materials |
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