- Apigenin 7-glucoside
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- $0.00 / 25kg
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2024-04-12
- CAS:578-74-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
- Apigenin 7-glucoside
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- $0.00 / 25kg
-
2023-09-13
- CAS:578-74-5
- Min. Order: 25kg
- Purity: 99%
- Supply Ability: 8 tons
- Apigenin 7-glucoside
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- $0.00 / 20mg
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2023-02-24
- CAS:578-74-5
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | Apigenin 7-glucoside Basic information |
| | Apigenin 7-glucoside Chemical Properties |
| Melting point | 230-237°C | | Boiling point | 788.9±60.0 °C(Predicted) | | density | 1.642±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) | | pka | 6.13±0.40(Predicted) | | color | Pale Yellow to Yellow | | BRN | 65669 | | Stability: | Hygroscopic | | InChIKey | KMOUJOKENFFTPU-YUVSVTSJNA-N | | SMILES | C1(C2=CC=C(O)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:17,20,22,24,r| | | LogP | -0.040 (est) | | CAS DataBase Reference | 578-74-5(CAS DataBase Reference) |
| Safety Statements | 34/35 | | WGK Germany | 3 | | F | 3-10 | | HS Code | 29389090 |
| | Apigenin 7-glucoside Usage And Synthesis |
| Uses | Apigenin 7-Glucoside is a by-product during the synthesis of Isorhoifolin (I819700), a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. | | Definition | ChEBI: A glycosyloxyflavone that is apigenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | | Application | Apigenin 7-glucoside is a flavonoid with anti-inflammatory and anxiolytic activities. It inhibits LPS-induced nitric oxide production in RAW 264.7 cells when used at concentrations ranging from 0.16 to 10 μM. In vivo, apigenin 7-glucoside (10 mg/kg) reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury. It also increases the number of entries and the time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic activity.
| | Biological Functions |
Apigenin 7-glucoside inhibited HL-60 cell growth, dose- and time-dependently, but did not cause apoptosis. The distribution of cells at different stages in the cell cycle indicated an accumulation of treated cells in the G2/M phase. Moreover, apigenin 7-glucoside induced granulocytic differentiation of HL-60 cells[1].
| | References | [1] Eri Nakazaki. “Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells.” European Journal of Nutrition 52 1 (2013): 25–35.
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| | Apigenin 7-glucoside Preparation Products And Raw materials |
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