Propargyl-PEG6-Ms manufacturers
- Propargyl-PEG5-Ms
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- $29.00 / 25mg
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2024-11-19
- CAS:1036204-62-2
- Min. Order:
- Purity: ≥98%
- Supply Ability: 10g
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| | Propargyl-PEG6-Ms Basic information |
| Product Name: | Propargyl-PEG6-Ms | | Synonyms: | Propargyl-PEG6-Ms;Propargyl-PEG5-Ms;PropargylPEG5Ms,PROTAC Linkers,Inhibitor,inhibit,Propargyl-PEG-5-Ms,Propargyl PEG5 Ms;Propargyl-PEG5-Ms/3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol, 1-methanesulfonate;2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethyl methanesulfonate;3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol, 1-methanesulfonate | | CAS: | 1036204-62-2 | | MF: | C14H26O8S | | MW: | 354.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1036204-62-2.mol |  |
| | Propargyl-PEG6-Ms Chemical Properties |
| Boiling point | 468.4±45.0 °C(Predicted) | | density | 1.171±0.06 g/cm3(Predicted) |
| | Propargyl-PEG6-Ms Usage And Synthesis |
| Description | Propargyl-PEG6-Ms is a PEG reagent that enables Click Chemistry reactions with azide-bearing compounds or biomolecules; copper is needed as a catalyst. The PEG spacer increases the water solubility of the reagent in aqueous environment. | | Uses | Propargyl-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Propargyl-PEG6-Ms Preparation Products And Raw materials |
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