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N,N-Dimethyltryptamine

N,N-Dimethyltryptamine Basic information
Product Name:N,N-Dimethyltryptamine
Synonyms:N,N-DIMETHYLTRYPTAMINE METHANOL*SOLUTION;1H-Indole-3-ethanamine, N,N-dimethyl-;2-(1H-Indol-3-yl)-N,N-dimethylethanamine;2-(3-Indolyl)ethyldimethylamine;2-(indol-3-yl)ethyldimethylamine;3-(2-(dimethylamino)ethyl)-indol;3-(2-Dimethylaminoethyl)indole;dmt(psychogenic)
CAS:61-50-7
MF:C12H16N2
MW:188.27
EINECS:200-508-4
Product Categories:Amines;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Isotope Labelled Compounds;Pharmaceutical Intermediates
Mol File:61-50-7.mol
N,N-Dimethyltryptamine Structure
N,N-Dimethyltryptamine Chemical Properties
Melting point 42-44°C
Boiling point bp 60-80°
density 1.0580 (rough estimate)
refractive index 1.5430 (estimate)
Fp 9℃
storage temp. Store at -20°C
solubility DMSO: soluble15mg/mL, clear
form powder
pka8.68 (ethanol-water)
color white to beige
NIST Chemistry ReferenceN,N-Dimethyltryptamine(61-50-7)
Safety Information
RIDADR 1544
WGK Germany 3
HazardClass 6.1(b)
PackingGroup III
Hazardous Substances Data61-50-7(Hazardous Substances Data)
DEA Controlled SubstancesCSCN: 7435
CAS SCH: I
NARC: N
MSDS Information
N,N-Dimethyltryptamine Usage And Synthesis
Chemical PropertiesTan Solid
UsesA labelled endogenous Sigma-1 receptor regulator.
UsesIt is an endogenous Sigma-1 receptor regulator.
DefinitionChEBI: A tryptamine derivative having two N-methyl substituents on the side-chain.
Synthesis Reference(s)The Journal of Organic Chemistry, 59, p. 3738, 1994 DOI: 10.1021/jo00092a046
General DescriptionDimethyltryptamine is a very weak hallucinogen, activeonly by inhalation or injection, with a short duration of action.It possesses pronounced sympathomimetic (NE) sideeffects.
Biological ActivityEndogenous σ 1 receptor ligand and psychoactive plant compound (K i = 14.8 μ M). Binding to σ 1 inhibits voltage-gated Na + channels and is responsible for the behavioral effects of DMT. Also a 5-HT 2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (K i = 4.0 μ M).
Tag:N,N-Dimethyltryptamine(61-50-7) Related Product Information
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