N,N-Dimethyltryptamine

N,N-Dimethyltryptamine Basic information

Product Name:	N,N-Dimethyltryptamine
Synonyms:	N,N-DIMETHYLTRYPTAMINE METHANOL*SOLUTION;1H-Indole-3-ethanamine, N,N-dimethyl-;2-(1H-Indol-3-yl)-N,N-dimethylethanamine;2-(3-Indolyl)ethyldimethylamine;2-(indol-3-yl)ethyldimethylamine;3-(2-(dimethylamino)ethyl)-indol;3-(2-Dimethylaminoethyl)indole;dmt(psychogenic)
CAS:	61-50-7
MF:	C12H16N2
MW:	188.27
EINECS:	200-508-4
Product Categories:	Amines;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Isotope Labelled Compounds;Pharmaceutical Intermediates
Mol File:	61-50-7.mol

N,N-Dimethyltryptamine Chemical Properties

Melting point	42-44°C
Boiling point	bp 60-80°
density	1.0580 (rough estimate)
refractive index	1.5430 (estimate)
Fp	9℃
storage temp.	Store at -20°C
solubility	DMSO: soluble15mg/mL, clear
form	powder
pka	8.68 (ethanol-water)
color	white to beige
NIST Chemistry Reference	N,N-Dimethyltryptamine(61-50-7)

Safety Information

RIDADR	1544
WGK Germany	3
HazardClass	6.1(b)
PackingGroup	III
Hazardous Substances Data	61-50-7(Hazardous Substances Data)
DEA Controlled Substances	CSCN: 7435 CAS SCH: I NARC: N

MSDS Information

N,N-Dimethyltryptamine Usage And Synthesis

Chemical Properties	Tan Solid
Uses	A labelled endogenous Sigma-1 receptor regulator.
Uses	It is an endogenous Sigma-1 receptor regulator.
Definition	ChEBI: A tryptamine derivative having two N-methyl substituents on the side-chain.
Synthesis Reference(s)	The Journal of Organic Chemistry, 59, p. 3738, 1994 DOI: 10.1021/jo00092a046
General Description	Dimethyltryptamine is a very weak hallucinogen, activeonly by inhalation or injection, with a short duration of action.It possesses pronounced sympathomimetic (NE) sideeffects.
Biological Activity	Endogenous σ 1 receptor ligand and psychoactive plant compound (K i = 14.8 μ M). Binding to σ 1 inhibits voltage-gated Na + channels and is responsible for the behavioral effects of DMT. Also a 5-HT 2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (K i = 4.0 μ M).

N,N-Dimethyltryptamine Preparation Products And Raw materials

Raw materials

N-Allyl-N-(2-fluorophenyl)amine-->1H-Indole-3-ethanamine, 5,6-dibromo-N,N-dimethyl--->1H-Indole-3-ethanamine, 5-[(2-methyl-2H-tetrazol-5-yl)methyl]--->5-BROMO-N,N-DIMETHYLTRYPTAMINE-->INDOLE-3-(N,N-DIMETHYL)GLYOXYLAMIDE-->TRYPTAMINE HYDROCHLORIDE-->2-Aminophenethanol-->INDOLE-3-(N,N-DIMETHYL)ACETAMIDE-->3-(2-BROMOETHYL)INDOLE-->Dimethylamine-->Methanol-->carbon monoxide-->Tryptamine-->N,N-Dimethylallylamine-->2-Dimethylaminoethanol-->Formaldehyde

Tag:N,N-Dimethyltryptamine(61-50-7) Related Product Information

Indometacin 1-METHYL-DL-TRYPTOPHAN 5-Methoxytryptamine 3-(2-Aminoethyl)-6-methoxyindole Dimethyl sulfate Dimethyl ether Dimethyl carbonate Dimethyl sulfoxide ETHANE Indole Indole-3-acetic acid Dimethyl sulfide Dimethyl fumarate N,N-Dimethylcyclohexylamine N,N-Dimethylformamide N,N-Dimethyldodecylamine N,N-Dimethylallylamine Tryptamine Dimethyltryptamine

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N,N-Dimethyltryptamine

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