- CALCIPOTRIOL MONOHYDRATE
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- $6.00 / 1KG
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2024-03-29
- CAS:147657-22-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | CALCIPOTRIOL MONOHYDRATE Basic information |
| Product Name: | CALCIPOTRIOL MONOHYDRATE | | Synonyms: | CALCIPOTRIOL MONOHYDRATE;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol hydrate;(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol monohydrate;1,3-Cyclohexanediol,5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-,hydrate (1:1), (1R,3S,5Z)-;Calcipotriol (Calcipotriene) Monohydrate;(1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol hydrate;Calcipotriol monohydrate CRS | | CAS: | 147657-22-5 | | MF: | C27H42O4 | | MW: | 430.63 | | EINECS: | 689-035-6 | | Product Categories: | API;API intermediates | | Mol File: | 147657-22-5.mol |  |
| | CALCIPOTRIOL MONOHYDRATE Chemical Properties |
| storage temp. | 4°C, protect from light, stored under nitrogen,unstable in solution, ready to use. | | solubility | Practically insoluble in water, freely soluble in ethanol (96 per cent), slightly soluble in methylene chloride. | | form | Powder | | Stability: | Hygroscopic, Light sensitive | | InChIKey | XBKHACNRWFKJNC-IZXATKCONA-N | | SMILES | C[C@]12CCC/C(=C\C=C3\C[C@@H](O)C[C@H](O)C\3=C)/[C@]1([H])CC[C@]2([H])[C@H](C)/C=C/[C@H](C1CC1)O.O |&1:1,10,13,17,21,23,27,r| |
| | CALCIPOTRIOL MONOHYDRATE Usage And Synthesis |
| Description | Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D3). Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response. Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes. | | Chemical Properties | White or almost white, crystalline powder. | | Uses | Vitamin D analogue. | | Definition | ChEBI: A hydrate that is the monohydrate form of calcipotriol. It is used in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients. |
| | CALCIPOTRIOL MONOHYDRATE Preparation Products And Raw materials |
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