- 5-Bromopentan-1-ol
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- $30.00 / 1KG
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2025-06-27
- CAS:34626-51-2
- Min. Order: 50KG
- Purity: 99%
- Supply Ability: 500000kg
- 5-Bromopentan-1-ol
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- $0.00 / 1kg
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2025-06-20
- CAS:34626-51-2
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20 tons
- 5-Bromopentan-1-ol
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- $1.00 / 1KG
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2019-07-12
- CAS:34626-51-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 25kg
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| | 5-Bromopentan-1-ol Basic information |
| | 5-Bromopentan-1-ol Chemical Properties |
| Boiling point | 117 °C / 20mmHg | | density | 1,38 g/cm3 | | refractive index | n20/D 1.482 | | Fp | 40 - 50°C | | storage temp. | 2-8°C | | pka | 15.11±0.10(Predicted) | | form | clear liquid | | color | Light red to Yellow to Red | | InChI | InChI=1S/C5H11BrO/c6-4-2-1-3-5-7/h7H,1-5H2 | | InChIKey | WJVQJXVMLRGNGA-UHFFFAOYSA-N | | SMILES | C(O)CCCCBr | | CAS DataBase Reference | 34626-51-2(CAS DataBase Reference) | | EPA Substance Registry System | 1-Pentanol, 5-bromo- (34626-51-2) |
| Hazard Codes | Xn | | Risk Statements | 36/37/38-22-10 | | Safety Statements | 26-36/37/39 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 3 | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | Ⅲ | | HS Code | 29055900 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| | 5-Bromopentan-1-ol Usage And Synthesis |
| Chemical Properties | Light yellow liquid | | Uses | 5-Bromopentanol is an organic building block that has been used as a reactant in the synthesis of 3-hydroxypyridine-2-thione to be used as a zinc binding group for histone deacetylase(HDAC) inhibition. | | Synthesis Reference(s) | Tetrahedron, 27, p. 5979, 1971 DOI: 10.1016/S0040-4020(01)91762-4 | | Synthesis | General procedure for the synthesis of 5-bromo-1-pentanol from 1,5-pentanediol: 1,5-pentanediol (14 g, 0.135 mol), 40% hydrobromic acid (28 mL, 0.2 mol), and 60 mL of benzene were added to a 250 mL three-necked flask, and reacted for 15 h in an oil bath at 70-80 °C. The reaction progress was monitored by TLC until the raw material spots disappeared. After completion of the reaction, the reaction mixture was washed sequentially with 5% sodium hydroxide solution, 10% hydrochloric acid and saturated saline, and then dried with anhydrous sodium sulfate. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, V/V = 8:1) and concentrated to give 5-bromo-1-pentanol (20.1 g, 89.1% yield) as colorless to light yellow liquid. | | References | [1] Patent: CN105766907, 2016, A. Location in patent: Paragraph 0026; 0041; 0042
[2] RSC Advances, 2015, vol. 5, # 37, p. 29114 - 29120
[3] Chemistry - A European Journal, 2015, vol. 21, # 30, p. 10721 - 10728
[4] Journal of Physical Chemistry, 1995, vol. 99, # 32, p. 12195 - 12203
[5] Organic Process Research and Development, 2003, vol. 7, # 3, p. 339 - 340 |
| | 5-Bromopentan-1-ol Preparation Products And Raw materials |
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