| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-SUMO-1
Purity:affinity isolated antibody, buffered aqueous solution Package:200μL Remarks:S8070
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| | ANTI-GMP-1 Basic information |
| Product Name: | ANTI-GMP-1 | | Synonyms: | ANTI-PIC1;ANTI-SENTRIN-1;ANTI-SMT3;ANTI-SMALL UBIQUITIN-RELATED MODIFIER-1;ANTI-SMALL UBIQUITIN-RELATED MODIFIIER-1;ANTI-SUMO-1;ANTI-SUMO-1 (C-TERMINAL);ANTI-UBL-1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-GMP-1 Structure]() |
| | ANTI-GMP-1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-GMP-1 Usage And Synthesis |
| Uses | Anti-SUMO-1 antibody produced in rabbit has been used in immunoblotting assay. | | General Description | The SUMO-1 (small ubiquitin-like modifier 1) gene is mapped to human chromosome 2q33.1 and is highly conserved. The protein structure includes an α-helix core surrounded by four-stranded β-sheets. | | Biochem/physiol Actions | SUMO (small ubiquitin-like modifier) proteins are associated with a number of cellular processes. SUMOylation mediated by SUMO1 is involved in nuclear transport mechanism, apoptosis, regulation of cyclin-dependent kinase 6 and protein stability. SUMO1 regulates tumor suppressor p53 protein, a transcription factor that is termed as the “guardian of the genome” plays a key role in the cell cycle events. Unlike ubiquitination which directs proteins for degradation, SUMOylation aims to alter the stability, localization and the function of the target protein. |
| | ANTI-GMP-1 Preparation Products And Raw materials |
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