|
|
| | Dimethyldioctadecylammonium bromide Basic information |
| | Dimethyldioctadecylammonium bromide Chemical Properties |
| Melting point | ~160 °C | | density | 1.047 | | refractive index | 1.5260 (estimate) | | RTECS | RG0185984 | | storage temp. | -20°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Hexanes (Slightly, Heated) | | form | Granular Powder | | color | White | | BRN | 3580323 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChI | InChI=1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1 | | InChIKey | PSLWZOIUBRXAQW-UHFFFAOYSA-M | | SMILES | C(CCCCCCCCCCCCCCCCC)[N+](C)(C)CCCCCCCCCCCCCCCCCC.[Br-] | | CAS DataBase Reference | 3700-67-2(CAS DataBase Reference) | | EPA Substance Registry System | 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, bromide (3700-67-2) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38-43 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | TSCA | Yes | | HazardClass | 9 | | HS Code | 29211990 |
| | Dimethyldioctadecylammonium bromide Usage And Synthesis |
| Description | 18:0 DDAB is a double-chained quaternary ammonium surfactant with a bromide counter ion. | | Chemical Properties | white powder | | Uses | Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV). | | General Description | 18:0 DDAB is cationic lipid and a quaternary ammonium salt. The hydrocarbon tails are saturated unlike the ionizable lipids. | | Biochem/physiol Actions | 18:0 DDAB is a surface-active molecule, used as an adjuvant to induce systemic immune response. It is non-toxic. | | Purification Methods | Crystallise the bromide from acetone, then MeOH [Lukac J Am Chem Soc 106 4387 1984]. Also purify it by chromatography on alumina by washing with *C6H6 and eluting with Me2CO, evaporating and crystallising from MeCN [Swain & Kreevoy J Am Chem Soc 77 1126 1955]. [Beilstein 4 IV 829.] |
| | Dimethyldioctadecylammonium bromide Preparation Products And Raw materials |
|