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(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME

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Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:667463-85-6
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: career henan chemical co
Tel: +86-0371-86658258 15093356674;
Email: factory@coreychem.com
Products Intro: Product Name:(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
CAS:667463-85-6
Purity:95--99% Package:1KG;1USD
Company Name: SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Products Intro: Product Name:BIO-acetoxime GSK3 Inhibitor IX2
CAS:667463-85-6
Purity:98% Package:Package as requetsed
Company Name: Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Tel: +86-86-22-87899925 +86-8618522618860
Email: 18522618860@163.com
Products Intro: Product Name:BIO-acetoxime GSK3 Inhibitor IX2
CAS:667463-85-6
Purity:0.99 Package:Various Packaging; segregation
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:BIO-acetoxime (GSK-3 Inhibitor X; BIA)
CAS:667463-85-6
Purity:98% Package:5mg Remarks:V0228

(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME manufacturers
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Basic information
Product Name:(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME
Synonyms:(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME;BIO-ACETOXIME;GSK-3 INHIBITOR X;(3Z)-3-[(3E)-3-[(Acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-Indol-2-one;6-Bromoindirubin acetoxime;6-Bromoindirubin-3′-acetoxime;GSK3 Inhibitor IX2;BIO-acetoxime(GSK-3 Inhibitor)
CAS:667463-85-6
MF:C18H12BrN3O3
MW:398.21
EINECS:200-258-5
Product Categories:Other enzyme inhibitors and activators
Mol File:667463-85-6.mol
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Structure
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Chemical Properties
density 1.69±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility H2O: soluble2mg/mL (clear solution, warmed)
form powder
pka9.22±0.20(Predicted)
color dark red to purple
Safety Information
Hazard Codes Xn,N
Risk Statements 22-50/53
Safety Statements 60-61
RIDADR UN 3077 9 / PGIII
WGK Germany 3
MSDS Information
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Usage And Synthesis
UsesBIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. It also induces Wnt signaling and inhibits CD8+ T cell effector differentiation.
Biological ActivitySelective GSK-3 α / β inhibitor (IC 50 values are 0.01, 2.4, 4.3 and 63 μ M for GSK-3 α / β , CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation.
storageStore at +4°C
(2'Z,3'E)-6-BROMOINDIRUBIN-3'-ACETOXIME Preparation Products And Raw materials
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