- Octanoyl chloride
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- $1.00 / 200KG
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2024-04-23
- CAS:111-64-8
- Min. Order: 25KG
- Purity: 99%
- Supply Ability: 2tons
- Octanoyl chloride
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- $10.00 / 1Kg
-
2023-11-02
- CAS:111-64-8
- Min. Order: 1Kg
- Purity: 98%
- Supply Ability: 1kg;5kg;10kg;100kg;1000kg...
- Octanoyl chloride
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- $0.00 / 1kg
-
2023-09-12
- CAS:111-64-8
- Min. Order: 1kg
- Purity: 99.00%
- Supply Ability: 20tons
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| | Octanoyl chloride Basic information |
| | Octanoyl chloride Chemical Properties |
| Melting point | -63 °C | | Boiling point | 195 °C (lit.) | | density | 0.953 g/mL at 25 °C (lit.) | | vapor pressure | 2.5 mm Hg ( 20 °C) | | refractive index | n20/D 1.435(lit.) | | Fp | 177 °F | | storage temp. | −20°C | | solubility | soluble in Chloroform, Methanol | | form | Liquid | | color | Clear | | Odor | pungent odor | | Water Solubility | REACTS | | Sensitive | Moisture Sensitive | | BRN | 635917 | | Stability: | Moisture sensitive | | CAS DataBase Reference | 111-64-8(CAS DataBase Reference) | | NIST Chemistry Reference | Octanoyl chloride(111-64-8) | | EPA Substance Registry System | Octanoyl chloride (111-64-8) |
| | Octanoyl chloride Usage And Synthesis |
| Chemical Properties | clear liquid | | Uses | Octanoyl chloride is used to produce adhesives. It is used as an acylating agent for a variety of compounds such as sugars (e.g. Sucrose, aromatic compounds (e.g. Anisole and monoglycerides. | | Uses | Applications of octanoyl chloride include:
- Synthesis of (R)-2-propyloctanoic acid, a therapeutic agent for Alzheimer′s disease.
- Synthesis of a variety of N-n-octyl-D-gluconamide based organogels.
- Building 2-heptylbenzo[d]thiazole moiety to synthesize conjugated copolymer with fluorine, as cathode interlayer in inverted polymer solar cells (PSCs).
- Octanoyl chloride is one of the essential precursors in the total synthesis of (?)-mandelalide L, a marine macrolide that display significant cytotoxicity against human cancer cell lines.
| | Preparation | Diphosgene (108.8 g) was added to a mixture of octanoic acid (144.2 g) and DMF (1.5 L) at 70 C°. The mixture was left to stand for 1 h, and then nitrogen was bubbled through it for 30 min at 100 C° to give 96.9% of octanoyl chloride (purity 99.99%). Benzoyl chloride and terephthaloyl chloride were similarly prepared. | | General Description | Clear colorless to straw-colored liquid with a pungent odor. | | Air & Water Reactions | Reacts vigorously with water to form HCl and caprylic acid. Insoluble in water. | | Reactivity Profile | Octanoyl chloride is incompatible with bases (including amines), water, alcohols, and with oxidizing agents . May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. | | Fire Hazard | Octanoyl chloride is combustible. |
| | Octanoyl chloride Preparation Products And Raw materials |
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