| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:UNC9975
CAS:1354030-19-5
Purity:99.00% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:UNC9975
CAS:1354030-19-5
Purity:99.02% Package:1mg/RMB 1980;5mg/RMB 4920;10mg/RMB 7130
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1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro- manufacturers
- UNC9975
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- $293.00 / 1mg
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2025-11-09
- CAS:1354030-19-5
- Min. Order:
- Purity: 98.78%
- Supply Ability: 10g
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| | 1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro- Basic information |
| Product Name: | 1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro- | | Synonyms: | 1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro-;UNC9975;UNC-9975 | | CAS: | 1354030-19-5 | | MF: | C23H28Cl2N4O2 | | MW: | 463.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1354030-19-5.mol | ![1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro- Structure](CAS/20210305/GIF/1354030-19-5.gif) |
| | 1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro- Chemical Properties |
| Boiling point | 651.5±65.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | pka | 8.68±0.10(Predicted) |
| | 1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro- Usage And Synthesis |
| Description | UNC9975 is a novel β-arrestin-biased D2R agonist. UNC9975 is an analog of aripiprazole and is a β-arrestin–biased dopamine D2 receptor ligand. Functionally selective, β-arrestin-biased D(2)R ligands represent valuable chemical probes for further investigations of D(2)R signaling in health and disease. | | Uses | UNC9975 is a D2R agonist that displays signaling bias via β-arrestin–ergic signaling and a simultaneously antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9975 can be utilized in antipsychotic research[1]. | | References | [1] Allen JA, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18488-93. DOI:10.1073/pnas.1104807108 |
| | 1,8-Naphthyridin-2(1H)-one, 7-[4-[4-(2,3-dichlorophenyl)hexahydro-1H-1,4-diazepin-1-yl]butoxy]-3,4-dihydro- Preparation Products And Raw materials |
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