| Company Name: |
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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029-86217788 13892832556 |
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| Products Intro: |
Product Name:Hydroxy-PEG3-acrylate
CAS:16695-45-7
Purity:95% HPLC Package:1g;5g;10g;25g;100g;1kg
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| | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate Basic information |
| Product Name: | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate | | Synonyms: | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate;Acrylic acid 2-[2-(2-hydroxyethoxy)ethoxy]ethyl ester;Triethylene glycol monoacrylate;Einecs 240-741-9;2-Propenoic acid,2-[2-(2-hydroxyethoxy)ethoxy]ethyl ester;Hydroxy-PEG3-acrylate;2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL PROP-2-ENOATE | | CAS: | 16695-45-7 | | MF: | C9H16O5 | | MW: | 204.22 | | EINECS: | 2407419 | | Product Categories: | | | Mol File: | 16695-45-7.mol | ![2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate Structure](CAS/GIF/16695-45-7.gif) |
| | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate Chemical Properties |
| Boiling point | 302.4±22.0 °C(Predicted) | | density | 1.098±0.06 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 14.36±0.10(Predicted) |
| | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate Usage And Synthesis |
| Description | Hydroxy-PEG3-acrylate is a PEG linker containing a hydroxyl group and an acrylate group. The hydroxyl group allows for further derivatization of the compound. The acrylate group enables Michael addition reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | Hydroxy-PEG3-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl acrylate Preparation Products And Raw materials |
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