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1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]-

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1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:ARN-6039；ARN 6039;ARN6039
CAS:1675206-11-7
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Suzhou ARTK Medchem Co., Ltd.
Tel: +8618168183658
Email: sales1@artkmedchem.com
Products Intro: Product Name:ARN-6039
CAS:1675206-11-7
Purity:0.98 Package:100KG;25KG;10KG;1KG
Company Name: PharmaBlock Sciences (Nanjing), Inc.  
Tel: 4000255188
Email: sun_dan@PharmaBlock.com
Products Intro: Product Name:ARN-6039
CAS:1675206-11-7
Purity:97% Package:1G;5G;10G;100G;250G
1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]- Basic information
Product Name:1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]-
Synonyms:1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]-;ARN 6039;ARN6039;ARN-6039
CAS:1675206-11-7
MF:C21H21F3N2O3
MW:406.4
EINECS:
Product Categories:
Mol File:1675206-11-7.mol
1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]- Structure
1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]- Chemical Properties
Boiling point 561.5±50.0 °C(Predicted)
density 1.322±0.06 g/cm3(Predicted)
pka2.84±0.20(Predicted)
Safety Information
MSDS Information
1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]- Usage And Synthesis
DescriptionARN-6039 (being developed by Arrien), is a Potent, Orally Available Inverse Agonist of RORgammat for Autoimmune Neuroinflammatory Demyelinating Disease. The activity of ARN-6039 against ROR?t was demonstrated in a ROR?t-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 release from CD4+T cell assays (220 nM). The compound also possesses ideal CNS drug-like criteria, exhibited excellent pharmacokinetics (%F: 37), pharmacodynamics, and correlative PK/PD and ADME characteristics.
1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]- Preparation Products And Raw materials
Tag:1H-Inden-1-one, 2,3-dihydro-6-methoxy-5-(4-morpholinyl)-2-[[3-(trifluoromethyl)-2-pyridinyl]methyl]-(1675206-11-7) Related Product Information