Argyrin F

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Argyrin F Suppliers list
Company Name: Zhejiang Huida Biotech Co., LTD  
Tel: 0571-89903022 18679456698
Email: zilong@hizyme.com
Argyrin F Basic information
Product Name:Argyrin F
Synonyms:Argyrin F;Cyclo[D-alanyl-2,3-didehydroalanyl-N-methylglycyl-2-[(1R)-1-amino-2-hydroxyethyl]-4-thiazolecarbonyl-L-tryptophyl-4-methoxy-L-tryptophylglycyl]
CAS:444300-74-7
MF:C40H44N10O9S
MW:840.91
EINECS:
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Mol File:444300-74-7.mol
Argyrin F Structure
Argyrin F Chemical Properties
Boiling point 1423.9±65.0 °C(Predicted)
density 1.48±0.1 g/cm3(Predicted)
pka12.26±0.70(Predicted)
Safety Information
MSDS Information
Argyrin F Usage And Synthesis
UsesArgyrin F a cyclic peptide with antitumoral activities. Argyrin F inhibits cell proliferation, migration, invasion and colony formation by partial induction of apoptosis and epithelial-mesenchymal transition (EMT). Argyrin F stabilizes p27kip, up-regulated p21waf1/cip1 and depletes COX2. Argyrin F can be used for the study of pancreatic ductal adenocarcinoma (PDAC)[1].
References[1] Chen X, et al. Therapeutic effects of Argyrin F in pancreatic adenocarcinoma. Cancer Lett. 2017 Jul 28;399:20-28. DOI:10.1016/j.canlet.2017.04.003
Argyrin F Preparation Products And Raw materials
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