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L-5-Hydroxytryptophan

L-5-Hydroxytryptophan Suppliers list
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Products Intro: Product Name:L-5-Hydroxytryptophan
CAS:4350-09-8
Purity:98% Package:1KG;10kg;25kg;100kg
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CAS:4350-09-8
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CAS:4350-09-8
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CAS:4350-09-8
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Products Intro: Product Name:L-5-Hydroxytryptophan
CAS:4350-09-8
Purity:99% Package:25KG

L-5-Hydroxytryptophan manufacturers

  • L-5-Hydroxytryptophan
  • L-5-Hydroxytryptophan pictures
  • $18.00 / 25g
  • 2024-02-23
  • CAS:4350-09-8
  • Min. Order: 25g
  • Purity: 0.99
  • Supply Ability: 100kg
  • L-5-Hydroxytryptophan
  • L-5-Hydroxytryptophan pictures
  • $1.00 / 1ASSAYS
  • 2024-02-23
  • CAS:4350-09-8
  • Min. Order: 1g
  • Purity: 99.99%+
  • Supply Ability: 20T
L-5-Hydroxytryptophan Basic information
Product Name:L-5-Hydroxytryptophan
Synonyms:L-5-HYDROXYTRYPTOPHAN HYDRATE;L-5-HYDROXYTRYPTOPHAN;2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONIC ACID;(-)-5-HYDROXY-L-TRYPTOPHAN;5-HYDROXY-L-TRP-OH;pretonine;L-5-Hydroxytryptophan, 99% 5GR;L-5-HTP, L-2-Amino-3-(5-hydroxyindolyl)propionic acid
CAS:4350-09-8
MF:C11H12N2O3
MW:220.22
EINECS:224-411-1
Product Categories:Amino Acids;Biochemistry;Biological-modified Amino Acids;Indoles;Tryptophans;Natural Plant Extract;Amino acidsPeptide Synthesis;Biochemicals Found in Plants;Nutrition Research;Indoles and derivatives;Tryptophan [Trp, W];Pharmaceutical Raw Materials;Inhibitors;natural product;amino;Other APIs;Amines, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Amines;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Metabolites & Impurities;Pharmaceuticals;Tryptophan Derivatives;Unnatural Amino Acid Derivatives;4350-09-8
Mol File:4350-09-8.mol
L-5-Hydroxytryptophan Structure
L-5-Hydroxytryptophan Chemical Properties
Melting point 270 °C (dec.) (lit.)
alpha -32.5 º (c=1,H2O on dry basis)
Boiling point 361.16°C (rough estimate)
density 0.902 g/mL at 25 °C (lit.)
refractive index n20/D 1.4850(lit.)
Fp 175 °F
storage temp. 2-8°C
solubility H2O: 10 mg/mL
form solid
pka2.22±0.10(Predicted)
color white
optical activity[α]22/D 30°, c = 1 in H2O
Water Solubility Slightly soluble
Merck 14,4847
BRN 88200
LogP-0.140 (est)
CAS DataBase Reference4350-09-8(CAS DataBase Reference)
EPA Substance Registry SystemL-5-Hydroxytryptophan (4350-09-8)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38-65-20/21/22-20/21
Safety Statements 36-26
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS YN7110000
3-10
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29339990
MSDS Information
ProviderLanguage
L-5-Hydroxytryptophan English
SigmaAldrich English
ACROS English
ALFA English
L-5-Hydroxytryptophan Usage And Synthesis
Chemical Propertieswhite to pale grey powder
Uses5-Hydroxy-L-Tryptophan is a hydroxylated metabolite of L-Tryptophan
UsesA labelled metabolite of Tryptophan
Uses5-Hydroxy-L-tryptophan has been used:
  • to inject experimental mice for serotonin detection
  • as a precursor of 5-hydroxytryptamine and injected in pregnant mice and neonatal rats for vital neutral red staining of lung slices
  • as a standard in citrate-acetate buffer for its use in high performance liquid chromatography (HPLC) analysis

DefinitionChEBI: 5-hydroxy-L-tryptophan is the L-enantiomer of 5-hydroxytryptophan. It has a role as a human metabolite, a plant metabolite and a mouse metabolite. It is a 5-hydroxytryptophan, a hydroxy-L-tryptophan and a non-proteinogenic L-alpha-amino acid. It is an enantiomer of a 5-hydroxy-D-tryptophan. It is a tautomer of a 5-hydroxy-L-tryptophan zwitterion.
General DescriptionColorless to pale pink crystals.
Air & Water ReactionsL-5-Hydroxytryptophan is sensitive to air. Slightly water soluble .
Reactivity ProfileL-5-Hydroxytryptophan reacts with bases. .
Fire HazardFlash point data for L-5-Hydroxytryptophan are not available, however, L-5-Hydroxytryptophan is probably combustible.
Trade nameLevothym (Promonta Lundbeck, Germany), Lévotonine (Panpharma, France), Oxyfan (Coli, Italy), Tript-OH (Sigma- Tai, Italy).
Biochem/physiol ActionsHydroxylation of L-tryptophan occurs in the brain during serotonin synthesis. This is a step that controls the production of serotonin and also yields 5-hydroxy-l-tryptophan (5-HTP) as a metabolite. Thus, consumption 5-HTP, increases the serotonin level, which might result in depression, lack of sleep and severe headache.
Purification MethodsLikely impurities are 5-hydroxy-D-tryptophan and 5-benzyloxytryptophan. Crystallise 5-hydroxy-L-tryptophan under nitrogen from water by adding EtOH. Store it under nitrogen. Also dissolve it in the minimum volume of hot H2O (~0.7g in 4mL) under nitrogen (charcoal) and allowed it to crystallise at 5o. The picrolonate crystallises from H2O with m 184-186o(dec). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2732-2737 1961, Morris & Armstrong J Org Chem 22 306 1957, Beilstein 22/14 V 278.]
L-5-Hydroxytryptophan Preparation Products And Raw materials
Preparation ProductsTryptamine
Tag:L-5-Hydroxytryptophan(4350-09-8) Related Product Information
GRIFFONIA SEED PLANT EXTRACT (5-HYDROXYTRYPTOPHAN) 10%~99%HPLC N-acetyl-6-hydroxytryptophan 5-HYDROXY-L-TRYPTOPHAN METHYL ESTER HYDROCHLORIDE,L-5-HYDROXYTRYPTOPHAN METHYL ESTER HYDROCHLORIDE POLYCLONAL ANTIBODY TO 5-HYDROXYTRYPTOPHAN (RABBIT),POLYCLONAL ANTI-CONJUGATED 5 HYDROXYTRYPTOPHAN ANTIBODIES,ANTI-5-HYDROXYTRYPTOPHAN Nα-Acetyl-5-hydroxytryptophan sodium salt 5-HYDROXY-L-TRYPTOPHAN, HYDROCHLORIDE,L-5-HYDROXYTRYPTOPHAN HYDROCHLORIDE,5-Hydroxy-L-Tryptophan,hydroxhloride N-[(tert-Butoxy)carbonyl]-D-tryptophan 5-hydroxy-dl-tryptophan crystalline*sigma grade,dl-hydroxytryptopha 5-HYDROXY-L-TRYPTOPHAN ETHYL ESTER HYDROCHLORIDE,L-5-HYDROXYTRYPTOPHAN ETHYL ESTER HYDROCHLORIDE HYDROXYTRYPTOPHAN, 5-(P) DL-5-hydroxytryptophan Mouse Monoclonal N-acetyl-5-hydroxy-L-tryptophan BOC-5-HYDROXY-DL-TRYPTOPHAN TRYPTOPHAN IMP. D (EP): (S)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID (5-HYDROXYTRYPTOPHAN) (±)-4-Hydroxytryptophan,4-hydroxy-DL-tryptophan L-5-Hydroxytryptophan HYDROXYTRYPTOPHAN, 5-(RG) CHLOROPHOSPHONAZO III