Geclosporin

Geclosporin Suppliers list
Company Name: Shenzhen Excellent Biotech Co., Ltd.
Tel: 13480692018
Email: ramyan@ex-biotech.com;sale@ex-biotech.com
Products Intro: Product Name:Cyclosporin G
CAS:74436-00-3
Purity:0.95 Package:10mg;25mg;50mg;100mg;250mg Remarks:QQ:3001349363
Company Name: BOC Sciences
Tel: 16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Geclosporin
CAS:74436-00-3
Package:$499/5mg Remarks:Geclosporin is an impurity of cycloporine, which is an immunosuppressant used in the treatment of rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, etc.
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008615858145714
Email: fandachem@gmail.com
Products Intro: Product Name:Geclosporin
CAS:74436-00-3
Purity:As coa Package:As request Remarks:74436-00-3
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Products Intro: Product Name:Cyclosporin G
CAS:74436-00-3
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: BOC Sciences
Tel: 1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Geclosporin
CAS:74436-00-3
Geclosporin Basic information
Product Name:Geclosporin
Synonyms:Cyclosporine Impurity G;Cyclosporin Impurity G;CS-2592;Cyclosporine G/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];Cyclosporine G;Geclosporin;(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Nva-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);Cyclo(((2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl)-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl)
CAS:74436-00-3
MF:C63H113N11O12
MW:1216.64
EINECS:
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Mol File:74436-00-3.mol
Geclosporin Structure
Geclosporin Chemical Properties
Melting point 196-197°
alpha D20 -245° (c = 1.0 in chloroform); D20 -191° (c = 1.04 in methanol)
Boiling point 1297.8±65.0 °C(Predicted)
density 1.013±0.06 g/cm3(Predicted)
pka13.32±0.70(Predicted)
Safety Information
MSDS Information
Geclosporin Usage And Synthesis
DescriptionGeclosporin is classified as Ciclosporins in medicine. The mechanism of action is its effect as immunosuppressants.
UsesCylclosporin G is a derivative of Cyclosporin A, an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
UsesCylclosporin G is a derivative of Cyclosporin A (C989900), an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Geclosporin Preparation Products And Raw materials
Tag:Geclosporin(74436-00-3) Related Product Information
Cyclosporin B Cyclosporin H CYCLOSPORIN D (3R,4R)-3-Hydroxy-5-[(E)-1-propenyl]cyclo[L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] Cyclosporin C CYCLOSPORIN J 1,1,4,7,10,10-HEXAMETHYLTRIETHYLENETETRAMINE Cyclosporine Cyclosporin A Geclosporin