| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
|
| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:UCB-5307
CAS:1515887-44-1
Purity:97% Package:100mg Remarks:S89895
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| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
|
| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:UCB-5307
CAS:1515887-44-1
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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1H-Benzimidazole-2-methanol, 1-[(2,5-dimethylphenyl)methyl]-α-4-pyridinyl- manufacturers
- UCB-5307
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- $51.00 / 1mg
-
2025-11-10
- CAS:1515887-44-1
- Min. Order:
- Purity: 99.89%
- Supply Ability: 10g
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| | 1H-Benzimidazole-2-methanol, 1-[(2,5-dimethylphenyl)methyl]-α-4-pyridinyl- Basic information |
| | 1H-Benzimidazole-2-methanol, 1-[(2,5-dimethylphenyl)methyl]-α-4-pyridinyl- Chemical Properties |
| Boiling point | 607.5±55.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | storage temp. | 4°C, away from moisture and light | | solubility | DMSO : 50 mg/mL (145.59 mM; Need ultrasonic) | | pka | 12.04±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | 1H-Benzimidazole-2-methanol, 1-[(2,5-dimethylphenyl)methyl]-α-4-pyridinyl- Usage And Synthesis |
| Uses | UCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex[1]. | | References | [1] O'Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795. DOI:10.1038/s41467-019-13616-1 |
| | 1H-Benzimidazole-2-methanol, 1-[(2,5-dimethylphenyl)methyl]-α-4-pyridinyl- Preparation Products And Raw materials |
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