| Company Name: |
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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18521735133 18521732826; |
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market@aladdin-e.com |
| Products Intro: |
Product Name:3′-Dephosphocoenzyme A
CAS:3633-59-8
Purity:>=90% Package:25mg/RMB 4393.00;5mg/RMB 2999.90;1mg/RMB 899.90
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:3'-Dephosphocoenzyme A
CAS:3633-59-8
Purity:>=90% (HPLC) Package:25MG Remarks:D3385-25MG
|
| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:3’-Dephosphocoenzyme A
CAS:3633-59-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | 3'-DEPHOSPHOCOENZYME A Basic information |
| | 3'-DEPHOSPHOCOENZYME A Chemical Properties |
| density | 1.85±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Water: 50 mg/ml | | form | A crystalline solid | | pka | 1.16±0.50(Predicted) |
| | 3'-DEPHOSPHOCOENZYME A Usage And Synthesis |
| Description | 3''-Dephosphocoenzyme A is an intermediate in the biosynthesis of coenzyme A (CoA; Item Nos. 16147 | 21499 | 21722) from pantothenic acid (vitamin B5; ). It is phosphorylated by CoA synthase in humans to form CoA. 3''-Dephosphocoenzyme A can be used as a transcription initiator in the synthesis of CoA-RNA by in vitro transcription. | | Uses | Dephosphocoenzyme A is the direct precursor of coenzyme A. It is used for the synthesis of coenzyme A by bifunctional CoA Synthase (CoASy, 4′-phosphopantetheine adenylyltransferase/dephospho-CoA kinase) which performs the transfer of the γ-phosphate of ATP to dephosphocoenzyme A. | | Definition | ChEBI: An adenosine 5'-phosphate that is coenzyme A in which the phosphate group at position 3' has been replaced by a hydrogen atom. It is an intermediate metabolite in pantothenate and CoA biosynthesis | | Biochem/physiol Actions | 3′-Dephosphocoenzyme A (DepCoA), also called desphosphoCoA (dpCoA), is synthesized from 4-phosphopantetheine by the enzyme phosphopanthetheine adenylyltransferase. It is an intermediate in coenzyme A biosynthetic pathway. In the presence of dephospho-CoA kinase (CoaE), dephosphocoenzyme A is converted to coenzyme A. 3′-Dephosphocoenzyme shares adenosine-diphosphate substructure as like the purines and is a non-canonical nucleotide and is an initiator of transcription initiation. It is routinely used in in vitro transcription studies to initiate RNA synthesis. |
| | 3'-DEPHOSPHOCOENZYME A Preparation Products And Raw materials |
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