| Company Name: |
Shanghai Chaolan Chemical Technology Center
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| Tel: |
QQ:65489617 15618227136 |
| Email: |
info@SuperLan-chem.com |
| Products Intro: |
Product Name:Nisoxetine
CAS:53179-07-0
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.com |
| Products Intro: |
Product Name:Nisoxetine
CAS:53179-07-0
Purity:详情请点击官网 Package:1 mg
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| Company Name: |
Princeton BioMolecular Research, Inc.
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| Tel: |
732 355 9920 ext. 102 |
| Email: |
info@princetonbio.com |
| Products Intro: |
Product Name:[3-(2-Methoxy-phenoxy)-3-phenyl-propyl]-methyl-amine
CAS:53179-07-0
Package:10g
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| | Nisoxetine Basic information |
| Product Name: | Nisoxetine | | Synonyms: | Nisoxetine;Compound 89218;[3-(2-Methoxy-phenoxy)-3-phenyl-propyl]-methyl-amine;Benzenepropanamine, γ-(2-methoxyphenoxy)-N-methyl- | | CAS: | 53179-07-0 | | MF: | C17H21NO2 | | MW: | 271.36 | | EINECS: | | | Product Categories: | | | Mol File: | 53179-07-0.mol |  |
| | Nisoxetine Chemical Properties |
| Boiling point | 404.8±40.0 °C(Predicted) | | density | 1.054±0.06 g/cm3(Predicted) | | pka | 10.16±0.10(Predicted) |
| | Nisoxetine Usage And Synthesis |
| Uses | Antidepressant. | | Definition | ChEBI: Nisoxetine is a secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group. It has a role as an antidepressant and an adrenergic uptake inhibitor. It is an aromatic ether and a secondary amino compound. | | General Description | Nisoxetine is a SNERI and is an antidepressant. Most activityresides in the β-isomer. | | Clinical Use | Nisoxetine was the initial phenoxyphenylpropylamine synthesized in the Lilly research laboratories
during the early 1970s from the rearrangement of an oxygen atom in diphenyhydramine, a
diphenylmethoxyethylamine, to a phenoxyphenylpropylamine. Nisoxetine was discovered to be a
potent and very selective SNRI, with little affinity for other receptors. It underwent clinical studies as an
alternative to Lilly's best-selling antidepressant, nortriptyline, but without the adverse effects associated with
the tricyclic secondary amines. It was never marketed, however, because of a greater interest in developing
its 4-trifluoromethyl analogue, fluoxetine, an SSRI. |
| | Nisoxetine Preparation Products And Raw materials |
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