| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:RapacuroniuM BroMide
CAS:156137-99-4
Package:50Mg,5Mg
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| Company Name: |
MedChemexpress LLC
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:RAPACURONIUM BROMIDE
CAS:156137-99-4
Purity:>98% Package:3000RMB/1mg
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| | Rapacuronium Basic information |
| Product Name: | Rapacuronium | | Synonyms: | Rapacuronium;Org 9487;Raplon;[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetyloxy-10,13-dimethyl-2-piperidin-1-yl-16-(1-prop-2-enylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate | | CAS: | 156137-99-4 | | MF: | C37H61BrN2O4 | | MW: | 677.81 | | EINECS: | | | Product Categories: | | | Mol File: | 156137-99-4.mol |  |
| | Rapacuronium Chemical Properties |
| Melting point | 184° | | alpha | 20D -12.7° (c = 1.01 in CHCl3) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 125 mg/mL (184.42 mM) |
| | Rapacuronium Usage And Synthesis |
| Description | Rapacuronium bromide was introduced in the US as a parenterally
administered adjunct to general anesthesia during surgical procedures. It is a
new steroidal derivative belonging to the same class as vecuronium bromide.
This 2,16-bispiperidinylandrostane derivative can be synthesized in 3 steps from
the 3-hydroxy-androstan-17-one analog and finally quaternized with allyl
bromide. Rapacuronium bromide is a nondepolarizing neuromuscular blocking
drug with a rapid onset and a short duration of action. With a relatively low
potency (ED90 = 1.15 mg/kg), Rapacuronium is expected to be substituted for
the polarizing succinylcholine with very short duration of action. | | Originator | Akzo Nobel (Netherlands) | | Uses | Rapacuronium Bromide is an aminosteroidal nondepolarizing neuromuscular blocking agent and was used as a anesthesia. | | Brand name | Raplon |
| | Rapacuronium Preparation Products And Raw materials |
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