|
|
| | Triethyl 2-fluoro-2-phosphonoacetate Basic information |
| | Triethyl 2-fluoro-2-phosphonoacetate Chemical Properties |
| Boiling point | 75 °C0.01 mm Hg(lit.) | | density | 1.194 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.425(lit.) | | Fp | 165 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | clear liquid | | color | Colorless to Almost colorless | | Specific Gravity | 1.194 | | BRN | 1912161 | | CAS DataBase Reference | 2356-16-3(CAS DataBase Reference) |
| Hazard Codes | Xi,F | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | F | 10-21 | | Hazard Note | Irritant | | HazardClass | IRRITANT, FLAMMABLE | | HS Code | 29319090 |
| | Triethyl 2-fluoro-2-phosphonoacetate Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | Reactant for:
- Diels-Alder reactions
- Biosynthesis of terpene
- Stereoselective synthesis of unsaturated esters, fluorides and nitriles from the reactions of aldehydes and ketones using Wadsworth-Emmons phosphonates
- Synthesis of quinolones
- Horner-Wadsworth-Emmons asymmetric hydration
- Addition reactions and the subsequent application to click chemistry
- Asymmetric intermolecular Stetter reactions
| | Synthesis Reference(s) | The Journal of Organic Chemistry, 60, p. 4730, 1995 DOI: 10.1021/jo00120a014 |
| | Triethyl 2-fluoro-2-phosphonoacetate Preparation Products And Raw materials |
|