| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine
CAS:2389988-53-6
Package:5mg;10mg;25mg
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| Company Name: |
Shanghai meikai technology co., ltd
|
| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine
CAS:2389988-53-6
Purity:98% Package:100mg;250mg;1g
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8H-Purin-8-one, 2-amino-7,9-dihydro-7-(2-propyn-1-yl)-9-β-D-xylofuranosyl- manufacturers
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| | 8H-Purin-8-one, 2-amino-7,9-dihydro-7-(2-propyn-1-yl)-9-β-D-xylofuranosyl- Basic information |
| | 8H-Purin-8-one, 2-amino-7,9-dihydro-7-(2-propyn-1-yl)-9-β-D-xylofuranosyl- Chemical Properties |
| Boiling point | 666.5±65.0 °C(Predicted) | | density | 1.693±0.06 g/cm3(Predicted) | | pka | 13.32±0.70(Predicted) |
| | 8H-Purin-8-one, 2-amino-7,9-dihydro-7-(2-propyn-1-yl)-9-β-D-xylofuranosyl- Usage And Synthesis |
| Uses | 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | 8H-Purin-8-one, 2-amino-7,9-dihydro-7-(2-propyn-1-yl)-9-β-D-xylofuranosyl- Preparation Products And Raw materials |
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