- Salicylanilide
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- $0.00 / 1KG
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2025-06-27
- CAS:87-17-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- Salicylanilide
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- $20.00 / 1kg
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2025-06-20
- CAS:87-17-2
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20 tons
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| | Salicylanilide Basic information |
| | Salicylanilide Chemical Properties |
| Melting point | 136-138 °C (lit.) | | Boiling point | 353.22°C (rough estimate) | | density | 1.1544 (rough estimate) | | bulk density | 455kg/m3 | | refractive index | 1.5700 (estimate) | | storage temp. | Store below +30°C. | | solubility | H2O: slightly soluble | | form | buffered aqueous glycerol solution | | pka | 7.11±0.10(Predicted) | | color | White to Almost white | | PH | 7-7.5 (50g/l, H2O, 25℃) | | biological source | goat | | Water Solubility | SLIGHTLY SOLUBLE | | Merck | 14,8330 | | BRN | 1108135 | | InChI | 1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) | | InChIKey | WKEDVNSFRWHDNR-UHFFFAOYSA-N | | SMILES | Oc1ccccc1C(=O)Nc2ccccc2 | | CAS DataBase Reference | 87-17-2(CAS DataBase Reference) | | NIST Chemistry Reference | Benzamide, 2-hydroxy-N-phenyl-(87-17-2) | | EPA Substance Registry System | Salicylanilide (87-17-2) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39-36 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 2 | | RTECS | VN7850000 | | Autoignition Temperature | >300 °C | | TSCA | TSCA listed | | HazardClass | 9 | | HS Code | 29242995 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | Salicylanilide Usage And Synthesis |
| Chemical Properties | greyish-brownish powder | | Uses | Anti-mildew, fungicide. | | Uses | antipyretic, fungicide | | Uses | Salicylanilides are compounds of varying biological activity ranging from anti-inflammatory agents to antiviral and antimicrobial agents. | | Definition | ChEBI: An amide of salicylic acid and of aniline; it is therefore both a salicylamide and an anilide. | | General Description | Salicylanilide inhibited mycobacterial isocitrate lyase (ICL) and showed a significant antimycobacterial effect. | | Hazard | Toxic by ingestion, irritant to skin. | | Synthesis | Method for catalyzing the carbonylation of halogenated aromatic hydrocarbons, amines, and carbon monoxide to prepare salicylanilides comprising the steps of:
(1) dehydrating and deoxidizing the catalyst and the reaction substrate
, sealed and standby.
(2) Treatment of reaction atmosphere
The reactor in step (1) will be ultrasonic 15-30min, high-purity carbon monoxide will be flushed into the ball gallbladder standby, ultrasonic completed with a mechanical pump to replace the atmosphere in the reactor to carbon monoxide gas.
(3) The above-treated reactor was placed on a stirrer for 4-30 hours, and when the reaction was completed, the mixture was taken out in a ventilated kitchen, centrifuged, and the supernatant, which was a mixed solution containing the target product salicylanilide, was analyzed qualitatively and quantitatively by GC-MS and GC for the samples to be tested.
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| | Salicylanilide Preparation Products And Raw materials |
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