| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Antiproliferative agent-7
CAS:2497687-47-3
Package:100mg/RMB 17500;50mg/RMB 13800;25mg/RMB 10600
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1-Propanamine, N,N-diethyl-3-[4-[4-phenyl-1-(phenylmethyl)-1H-1,2,3-triazol-5-yl]phenoxy]- manufacturers
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| | 1-Propanamine, N,N-diethyl-3-[4-[4-phenyl-1-(phenylmethyl)-1H-1,2,3-triazol-5-yl]phenoxy]- Basic information |
| | 1-Propanamine, N,N-diethyl-3-[4-[4-phenyl-1-(phenylmethyl)-1H-1,2,3-triazol-5-yl]phenoxy]- Chemical Properties |
| Boiling point | 600.4±65.0 °C(Predicted) | | density | 1.08±0.1 g/cm3(Predicted) | | pka | 10.17±0.25(Predicted) |
| | 1-Propanamine, N,N-diethyl-3-[4-[4-phenyl-1-(phenylmethyl)-1H-1,2,3-triazol-5-yl]phenoxy]- Usage And Synthesis |
| Uses | Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 can increase ROS production and induce apoptosis[1]. | | References | [1] Dheer D,et al.Design, synthesis and comparative analysis of triphenyl-1,2,3-triazoles as anti-proliferative agents. Eur J Med Chem. 2020 Dec 1;207:112813. DOI:10.1016/j.ejmech.2020.112813 |
| | 1-Propanamine, N,N-diethyl-3-[4-[4-phenyl-1-(phenylmethyl)-1H-1,2,3-triazol-5-yl]phenoxy]- Preparation Products And Raw materials |
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