| Company Name: |
Shanghai Chaolan Chemical Technology Center
|
| Tel: |
021-QQ：65489617 15618227136 |
| Email: |
Sales@ATKchemical.com |
| Products Intro: |
Product Name:Anti-inflammatory agent 54
CAS:2924156-46-5
Purity:98 Package:1G,5G,10G,50G,100G,500G
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Anti-inflammatory agent 54
CAS:2924156-46-5
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
|
Anti-inflammatory agent 54 manufacturers
|
| | Anti-inflammatory agent 54 Basic information |
| | Anti-inflammatory agent 54 Chemical Properties |
| density | 1.317±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 13.787±0.46(predicted) |
| | Anti-inflammatory agent 54 Usage And Synthesis |
| Uses | Anti-inflammatory agent 54 (compound 9c) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC50: 2.4 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model[1]. | | References | [1] Cui E, et al. Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents. J Nat Prod. 2023 Aug 25;86(8):1950-1959.. DOI:10.1021/acs.jnatprod.3c00309 |
| | Anti-inflammatory agent 54 Preparation Products And Raw materials |
|