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Feprazone

Feprazone Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-66670886
Email: info@dakenchem.com
Products Intro: Product Name:Feprazone
CAS:30748-29-9
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:Feprazone
CAS:30748-29-9
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Shanghai Yingrui Biopharma Co., Ltd.
Tel: +86-21-33585366 E-mail:sales03@shyrchem.com
Email: sales03@shyrchem.com
Products Intro: Product Name:Feprazone
CAS:30748-29-9
Purity:0.98 Package:100g;250g;500g;1kg
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Feprazone
CAS:30748-29-9
Purity:99% Package:1kg;1USD
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel: +8619930503282
Email: sales3@crovellbio.com
Products Intro: Product Name:Feprazone
CAS:30748-29-9
Purity:99% Package:1KG;10USD

Feprazone manufacturers

  • Feprazone
  • $1.90 / KG
  • 2021-08-28
  • CAS:30748-29-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 ton
  • Feprazone
  • $10.00 / KG
  • 2021-07-31
  • CAS:30748-29-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • Feprazone
  • $1.00-1.00 / KG
  • 2021-07-20
  • CAS:30748-29-9
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 50tons
Feprazone Basic information
Product Name:Feprazone
Synonyms:4-(2-isopentenyl)-1,2-diphenyl-3,5-pyrazolidinedione;Zepelin;1,2-diphenyl-4-(3-methyl-2-butenyl)-3,5-pyrazolidinedione;1,2-diphenyl-4-(3-methyl-2-butenyl)-5-pyrazolidinedione;fenilprenazone;methrazone;phenylprenazone;pheprazone
CAS:30748-29-9
MF:C20H20N2O2
MW:320.39
EINECS:250-324-3
Product Categories:
Mol File:30748-29-9.mol
Feprazone Structure
Feprazone Chemical Properties
Melting point 156.5° (ethanol)
Boiling point 459.28°C (rough estimate)
density 1.1670 (rough estimate)
refractive index 1.5700 (estimate)
pka5.09 ± 0.07(at 25℃)
CAS DataBase Reference30748-29-9(CAS DataBase Reference)
Safety Information
ToxicityLD50 in male mice, rats (mg/kg): 408.8, 386.4 i.p.; 1067, >2000 orally (Bianchi, Bonardi)
MSDS Information
Feprazone Usage And Synthesis
OriginatorZepelin,De Angeli,Italy,1972
UsesFeprazone is a anti-inflammatory agent used in the management of inflammatory or degenerative joint diseases.
Manufacturing Process43.8 g (0.237 mol) of hydrazobenzene are added to a solution of sodium ethylate obtained by dissolving 6.55 g (0.285 mol) of sodium in 125 ml of anhydrous ethanol. 59.6 g (0.2612 mol) of diethyl 3-methyl-2-butenyl malonate are then added, with stirring, at the reflux temperature.
The reaction mixture is refluxed for 1 hour, then the solvent is slowly distilled off, the distillation being completed in vacuo. The solid residue so obtained is dissolved in 400 ml of water and washed with ether. The solution is acidified with 10% HCl and the 1,2-diphenyl-3,5-dioxo-4-(3'-methyl-2'-butenyl)- pyrazolidine which separates is purified by crystallization from ethanol (MP 155°C to 156°C).
Brand nameBentudor;Brotazona;Cocresol;Da 2370;Danfenona;Feniprenazone;Fepramole;Golaman;Impremial;Metrazone;Naoven;Nazona;Nessazona;Prenakes;Rangozona;Represil;Solielin;Tbrien;Vapesin;Zontal;Zoontal.
Therapeutic FunctionAntiinflammatory
World Health Organization (WHO)Feprazone, a pyrazolone derivative with antiinflammatory, analgesic and antipyretic activity, was introduced in 1978 for the treatment of rheumatic disorders. As it is structurally related to phenylbutazone it is subjected to rigorously restricted indications by some national regulatory authorities. See WHO comment for phenylbutazone. WHO has been informed that to date feprazone is only available in some 7 countries.
Feprazone Preparation Products And Raw materials
Raw materialsSodium-->1,2-Diphenylhydrazine-->Ethanol
Tag:Feprazone(30748-29-9) Related Product Information
Bendazol Phenprobamate Etodolac Flumazenil LAPPACONITINE(P) (+/-)-Sulfinpyrazone Acetaminophen 1,2-Diphenylhydrazine Diniconazole FEPRAZONE Phenidone 1-Phenyl-4-methyl-3-pyrazolidone 1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE Feprazone Linezolid Uniconazole 3-Methyl-1-butene 3,3-Dimethylallyl bromide