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| | 2-Azabicyclo[2.2.1]hept-5-en-3-one Basic information |
| | 2-Azabicyclo[2.2.1]hept-5-en-3-one Chemical Properties |
| Melting point | 54-58 °C(lit.) | | Boiling point | 102-106 °C0.25 mm Hg(lit.) | | density | 1.1143 (rough estimate) | | vapor pressure | 0.3-1.06Pa at 25-40℃ | | refractive index | 1.5040 (estimate) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | pka | 15.48±0.20(Predicted) | | form | Crystalline Powder | | color | Off-white to beige | | Water Solubility | >1000 g/L (23 ºC) | | BRN | 508342 | | InChIKey | DDUFYKNOXPZZIW-UHFFFAOYSA-N | | LogP | -0.14 at 20℃ | | Surface tension | 69.9mN/m at 1g/L and 20℃ | | CAS DataBase Reference | 49805-30-3(CAS DataBase Reference) |
| | 2-Azabicyclo[2.2.1]hept-5-en-3-one Usage And Synthesis |
| Chemical Properties | solid | | Uses | 2-Azabicyclo[2.2.1]hept-5-en-3-one was used in:
- preparation of (3aS,4R,6R,6aR)-6-((methoxy-methoxy)methyl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-amine, a precursor of analog of bredinin
- synthesis of therapeutic drugs
- chemoenzymatic synthesis of (?)-carbovir
| | Uses | Intermediate for pharmaceuticals. Product Data Sheet | | Uses | Abacavir intermediate. 2-Azabicyclo[2.2.1]hept-5-en-3-one is used as an intermediate in the synthesis of carbocyclic sugar amines, carbanucleosides, and carbocyclic dinucleotide analogues. | | General Description | 2-Azabicyclo[2.2.1]hept-5-en-3-one is also referred as vince lactam. It is a versatile intermediate in the synthesis of carbocyclic nucleosides. 2-Azabicyclo[2.2.1]hept-5-en-3-one and its monohydrated complex was investigated in a supersonic jet by Fourier transform microwave spectroscopy. |
| | 2-Azabicyclo[2.2.1]hept-5-en-3-one Preparation Products And Raw materials |
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