| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Caspase-3 activator 4
CAS:1817874-62-6
Package:10mg;50mg
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| | Caspase-3 activator 4 Basic information |
| Product Name: | Caspase-3 activator 4 | | Synonyms: | Caspase-3 activator 4;1H-Indole-3-propanamide, α-[(2,2-di-1H-indol-3-yl-1-oxopropyl)amino]-N-methyl-β-oxo-, (αS)- | | CAS: | 1817874-62-6 | | MF: | C31H27N5O3 | | MW: | 517.58 | | EINECS: | | | Product Categories: | | | Mol File: | 1817874-62-6.mol |  |
| | Caspase-3 activator 4 Chemical Properties |
| Melting point | 220 °C | | Boiling point | 968.599±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.370±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 12.756±0.46(predicted) |
| | Caspase-3 activator 4 Usage And Synthesis |
| Uses | Caspase-3 activator 4 (compound 4o) is a potent and cross the blood-brain barrier caspase-3 activator. Caspase-3 activator 4 shows antiproliferative activity. Caspase-3 activator 4 induces apoptosis. Caspase-3 activator 4 increases the gene expression of TNF-α. Caspase-3 activator 4 decreases the protein expression of cleaved caspases 3/caspases 3[1]. | | IC 50 | Caspase 3 | | References | [1] Qin X, Xu W, Hu J, Dong Y, Ding R, Huang S, Zhao Z, Chang H, Wang X, Dong S. Structure-activity relationship study of Pseudellone C as anti-glioma agents by targeting TNF/TNFR signaling pathway. Eur J Med Chem. 2024 Aug 26;278:116799. DOI:10.1016/j.ejmech.2024.116799 |
| | Caspase-3 activator 4 Preparation Products And Raw materials |
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