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CHEMBRDG-BB 5280909

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CHEMBRDG-BB 5280909 Suppliers list
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:ML354
CAS:89159-60-4
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:ML 354
CAS:89159-60-4
Purity:>=98%(HPLC) Package:$141.9/10mg;$590.9/50mg;Bulk package Remarks:98%(HPLC)
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol(SALTDATA: FREE)
CAS:89159-60-4
Purity:95% Package:1G
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Products Intro: Product Name:ML354
CAS:89159-60-4
Purity:>=98% (HPLC) Package:25MG Remarks:SML1439-25MG
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Products Intro: Product Name:ML-354
CAS:89159-60-4
Purity:98% Package:1mg;5mg;10mg
CHEMBRDG-BB 5280909 Basic information
Product Name:CHEMBRDG-BB 5280909
Synonyms:CHEMBRDG-BB 5280909;(1-METHYL-5-NITRO-3-PHENYL-1H-INDOL-2-YL)METHANOL;(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol(SALTDATA: FREE);ML-354;1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol;1H-Indole-2-methanol, 1-methyl-5-nitro-3-phenyl-
CAS:89159-60-4
MF:C16H14N2O3
MW:282.29
EINECS:
Product Categories:
Mol File:89159-60-4.mol
CHEMBRDG-BB 5280909 Structure
CHEMBRDG-BB 5280909 Chemical Properties
Melting point 178-179 °C(Solv: 1,4-dioxane (123-91-1))
Boiling point 544.0±50.0 °C(Predicted)
density 1.29±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility ≤2mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
form powder
pka14.47±0.10(Predicted)
color white to beige
Safety Information
RIDADR UN 2811 6.1 / PGIII
MSDS Information
CHEMBRDG-BB 5280909 Usage And Synthesis
DescriptionML-354 is an indole-based, proteinase-activated receptor 4 (PAR4) antagonist (IC50 = 140 nM) that exhibits 71-fold selectivity for PAR4 over PAR1 (IC50 = 10 μM) in isolated human platelets.
UsesML-354 is a selective protease activated receptor 4 ( PAR-4) antagonist used for its antithrombotic effects.
Biochem/physiol ActionsML354 is a potent and selective PAR4 (protease activated receptor-4) antagonist.
IC 50140 nm
storageStore at -20°C
references[1]. wen, w., young, s., duvernay, m., schulte, m., nance, k., & melancon, b. et al. substituted indoles as selective protease activated receptor 4 (par-4) antagonists: discovery and sar of ml354. bioorganic & medicinal chemistry letters. 2014; 24(19): 4708-4713.
CHEMBRDG-BB 5280909 Preparation Products And Raw materials
Tag:CHEMBRDG-BB 5280909(89159-60-4) Related Product Information
5-AMINO-2-METHYLINDOLE 2,3-DIMETHYL-5-NITROINDOLE 2-METHYL-5-NITROINDOLE 2-methyl-3-phenyl-1H-indole 3-phenylindole (1-METHYL-1H-INDOL-2-YL)-METHANOL 5-AMINO-2,3-DIMETHYLINDOLE ETHYL 6-TERT-BUTYL-2-METHYLNICOTINATE 5-AMINO-1-N-METHYLINDOLE 1-METHYL-5-NITRO-1H-INDOLE CHEMBRDG-BB 5280909