- 3-Methylamino-1,2-propanediol
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- $32.00 / 1kg
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2024-03-23
- CAS:40137-22-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 3-Methylamino-1,2-propanediol Basic information |
| Product Name: | 3-Methylamino-1,2-propanediol | | Synonyms: | N-METHYL-3-AMINO-1,2-PROPANEDIOL;3-(AMINOMETHYL)-1,2-PROPANEDIOL;3-METHYLAMINO-PROPANE-1,2-DIOL;3-METHYLAMINO-1,2-PROPANEDIOL;2,3-Dihydroxy-N-methylpropylamine;3-Methylamino-1,2-Propandiol;N-Methyl-2,3-dihydroxypropylamine;1,2-Propanediol, 3-(methylamino)- | | CAS: | 40137-22-2 | | MF: | C4H11NO2 | | MW: | 105.14 | | EINECS: | 254-809-0 | | Product Categories: | Amino Alcohols;Organic Building Blocks;Oxygen Compounds;API;bc0001;40137-22-2 | | Mol File: | 40137-22-2.mol |  |
| | 3-Methylamino-1,2-propanediol Chemical Properties |
| Melting point | 69°C (estimate) | | Boiling point | 247 °C | | density | 1.095 g/mL at 20 °C(lit.) | | refractive index | n20/D 1.476 | | Fp | 152 °C | | storage temp. | Inert atmosphere,Room Temperature | | pka | 14.09±0.20(Predicted) | | form | clear liquid | | color | Colorless to Almost colorless | | Specific Gravity | 1.0921 | | PH | 11.5 (100g/l, H2O, 20℃) | | Water Solubility | miscible | | BRN | 1733341 | | CAS DataBase Reference | 40137-22-2(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | RIDADR | 2735 | | WGK Germany | 3 | | F | 3-10-34 | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29221980 | | Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
| | 3-Methylamino-1,2-propanediol Usage And Synthesis |
| Description | 3-Methylamino-1,2-propanediol (MAPD) is a clear liquid with the chemical formula C4H11NO2. It can be synthesized from allylamine and alkanolamine via a thermal process. It reacts with chloride to form methyl chloroacetate, which can then be converted into 3-methylamino-1,2-propanediol by reaction with methanol. The production process for this substance has been shown to generate low levels of hazardous substances such as polycyclic aromatic hydrocarbons (PAHs) and dioxins. | | Chemical Properties | clear colorless to pale yellow viscous liquid | | Uses | 3-Methylamino-1,2-propanediol is a reactive compound that is used in the synthesis of organic acids. It is also used as an intermediate in the manufacture of polyethylene glycols and particle coatings. | | Definition | ChEBI: 3-methylamino-1,2-propanediol is a secondary amine. | | Preparation | 3-Methylamino-1,2-propanediol (MAPD) is synthesized by reacting 3-chloro-1,2-propanediol (CPD) with
monomethyl amine in alkaline environment by adding sodium hydroxide.
Afterwards, the product undergoes a series of purification steps.
N-Methyl-1-amino-2,3-propandiol (45A) Methylamine (172ml of a 40% solution in water, 2 mol) was cooled to 0 °C and 2,3-epoxy-1-propanol (25g, 0.34mol) was added at a rate to maintain the temperature at or below 10 °C. The mixture was stirred for 3 hours at 0 °C. Excess methylamine and water was evaporated in vacuo and the product was purified by distillation at 103-105 °C, at 0.5 mm Hg, to give the compound 3-Methylamino-1,2-propanediol.
 | | Hazard | 3-Methylamino-1,2-propanediol is danger.
H314 (32.76%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H315 (67.24%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (65.52%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| | 3-Methylamino-1,2-propanediol Preparation Products And Raw materials |
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